Search for dissertations about: "Hematopoietic stem cell"
Showing result 6 - 10 of 246 swedish dissertations containing the words Hematopoietic stem cell.
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6. Consequences of Shb Deficiency on Hematopoietic Cell Function
Abstract : The adaptor protein Shb has been implicated in the signaling of several tyrosine kinase receptors and previous studies have suggested a role for Shb in the signal transduction of T cells. Shb associates with the T cell receptor (TCR) and partakes in the signal propagation of activated T lymphocytes. READ MORE
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7. Cellular and Molecular Pathways Governing Hematopoietic Stem Cell Fate
Abstract : Hematopoietic Stem Cells (HSCs) have been defined to have abilities of both self-renewal and multi-lineage differen-tiation. The balance between these abilities is rigorously controlled under steady-state status (homeostasis) and when the normal processes of self-renewal and differentiation become deregulated, a disorder of blood system (such as leukemias) can occur. READ MORE
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8. Exploring the heterogeneity of the hematopoietic stem and progenitor cell pool in cord blood
Abstract : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for a wide range of malignant and hereditary disorders. It is yet the only clinically established stem cell treatment. READ MORE
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9. Molecular regulation of hematopoietic stem cells
Abstract : Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). READ MORE
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10. Molecular Mechanisms in Hematopoietic Stem Cell Aging
Abstract : The blood is composed of many different cell types that through tightly regulated mechanisms are derived from hematopoietic stem cells (HSCs). In addition, HSCs are able to undergo self-renewing divisions whereby new HSCs are produced. READ MORE