Search for dissertations about: "Heme"

Showing result 16 - 20 of 140 swedish dissertations containing the word Heme.

  2. 16. Reaction Mechanisms of Metalloenzymes and Synthetic Model Complexes Activating Dioxygen : A Computational study

    Author : Valentin Georgiev; Per E.M. Siegbahn; Sam de Visser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; catalysis; density functional theory; extradiol; intradiol; dioxygenases; oxygen; biomimetic complexes; heme; spin transition; adipic acid; Chemical physics; Kemisk fysik; kvantkemi; Quantum Chemistry;

    Abstract : Quantum chemistry has nowadays become a powerful and efficient tool that can be successfully used for studies of biosystems. It is therefore possibleto model the enzyme active-site and the reactions undergoing into it, as well as obtaining quite accurate energetic profiles. READ MORE

  4. 17. The Physiological Cost of Antibiotic Resistance

    Author : Mirjana Macvanin; Diarmaid Hughes; Stanley Maloy; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; fusidic acid; fitness cost; protein synthesis; EF-G; ppGpp; RpoS; oxidative stress; heme; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : Becoming antibiotic resistant is often associated with fitness costs for the resistant bacteria. This is seen as a loss of competitiveness against the antibiotic-sensitive wild-type in an antibiotic-free environment. READ MORE

  5. 18. α1-microglobulin – Therapeutic opportunities in kidney and erythrocyte pathology

    Author : Amanda Kristiansson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; α1-microglobulin; oxidative stress; kidneys; heme; Red blood cells; hemolysis; radiation;

    Abstract : Oxidative stress is defined as an imbalance between oxidants and antioxidants. The reasons behind the condition are diverse, and can result in, or contribute to, the severity of many diseases. The body has different protective mechanisms to reduce the oxidative burden, among them a protein called α1-microglobulin (A1M). READ MORE

  6. 19. Bacterial cytochromes P450-Studies on Cytochrome P450 102A2 and P450 102A3 of Bacillus subtilis

    Author : Mattias Gustafsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; AbrB; Spo0A; monooxygenase; heme; Bacillus subtilis; Cytochrome P450; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Cytochromes P450 constitute a super-family of heme containing mixed function mono-oxygenases that is found in all branches of life. They introduce single oxygen atoms, mostly in the form of hydroxyl groups, into lipophilic substances and thereby render them more hydrophilic and susceptible to further reactions. READ MORE

  7. 20. Enzymatic metal-chelation by porphyrins

    Author : Andreas Hansson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tetrapyrrole; Plant biochemistry; Växtbiokemi; MIDAS; metallation; magnesium chelatase; integrin; heme; ferrochelatase; chlorophyll; barley; AAA ; ATPase;

    Abstract : This thesis deals with the structure and function of two different enzymes, ferrochelatase and magnesium chelatase, that catalyse similar reactions. When this work started, a three-dimensional model of ferrochelatase existed. Much was known about the enzyme, but some details remained unclear. READ MORE