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Showing result 1 - 5 of 60 swedish dissertations matching the above criteria.

  2. 1. Metabolism and Biological Monitoring of Organic Acid Anhydrides

    Author : Christian Lindh; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; human; distribution; analysis; biological monitoring; autoradiography; adducts; hemoglobin; plasma; urine; Hexahydrophthalic anhydride; methyltetrahydrophthalic anhydride; guinea pigs; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : The aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. READ MORE

  4. 2. Vitreoscilla hemoglobin. In vitro mutagenesis and transcript profiling to improve its biotechnological usefulness

    Author : Charlotte Andersson; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemical technology; Biokemisk teknik; gene expression analysis; transcript profiling; microarray; DNA chips; microaerobic; hypoxia; oxygen-limited; bacterial hemoglobin; Escherichia coli; Vitreoscilla hemoglobin VHb ;

    Abstract : Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. READ MORE

  5. 3. A thermostable alkaline protease from a new alkaliphilic Nesterenkonia sp

    Author : Shahrzad Bakhtiar; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; substrate specificity; crystallization; Biotechnology; Bioteknik; DNA-DNA hybridisation; 16S rDNA analysis; phenotypic characterisation; circular dichroism; differential scanning calorimetry; Nesterenkonia abyssinica; stability; calcium-independent; alkaline protease; alkaliphilic;

    Abstract : This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. READ MORE

  6. 4. Methodology for hemoglobin adduct measurement : Fetal exposures to acrylamide and other genotoxic agents

    Author : Hans von Stedingk; Margareta Törnqvist; Per Rydberg; Christian Lindh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; miljökemi; Environmental Chemistry;

    Abstract : There is increasing evidence that exposure to toxic chemicals during the prenatal period constitute a higher health risk than exposure during adulthood. To characterize exposure and identify risk factors, sensitive methods for analysis of chemicals in vivo with biomarker methods are needed. READ MORE

  7. 5. Disordered matter: From Ionic Glasses to Proteins

    Author : Charbel Tengroth; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; liquid-glass transition; PPG; disorder; B2O3; neutron scattering; hemoglobin; time-resolved resonance Raman scattering; CKN;

    Abstract : Understanding the glassy state is regarded as one of the ten most important questions in physics in the 21st century [1]. This thesis deals with structure and dynamics of a few model disordered systems ranging from an ionic glass to proteins. The structure of an ionic liquid, Ca0.4K0. READ MORE