Search for dissertations about: "Henrik Antti"

Showing result 6 - 10 of 10 swedish dissertations containing the words Henrik Antti.

2. 6. Metabolomics and proteomics studies of brain tumors : a chemometric bioinformatics approach

   Author : Lina Mörén; Henrik Antti; Anders Malmendal; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; glioma; meningioma; metabolomics; proteomics; mass-spectrometry; biologisk kemi; biological chemistry;

   Abstract : The WHO classification of brain tumors is based on histological features and the aggressiveness of the tumor is classified from grade I to IV, where grade IV is the most aggressive. Today, the correlation between prognosis and tumor grade is the most important component in tumor classification. READ MORE

4. 7. Diagnosis of acute and chronic enteric fever using metabolomics

   Author : Elin Näsström; Henrik Antti; Anders Johansson; Peter Spégel; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Enteric fever; Salmonella; chronic carriers; metabolomics; diagnosis; biomarkers; multivariate data analysis; GCxGC-MS; GC-MS; LC-MS;

   Abstract : Enteric (or typhoid) fever is a systemic infection mainly caused by Salmonella Typhi and Salmonella Paratyphi A. The disease is common in areas with poor water quality and insufficient sanitation. Humans are the only reservoir for transmission of the disease. READ MORE

5. 8. Multivariate profiling of metabolites in human disease : Method evaluation and application to prostate cancer

   Author : Elin Thysell; Henrik Antti; Janne Lehtiö; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; metabolomics; predictive metabolomics; mass spectrometry; GC-MS; biomarkers; chemometrics; design of experiments; multivariate data analysis; prostate cancer; bone metastases; plasma; biologisk kemi; biological chemistry;

   Abstract : There is an ever increasing need of new technologies for identification of molecular markers for early diagnosis of fatal diseases to allow efficient treatment. In addition, there is great value in finding patterns of metabolites, proteins or genes altered in relation to specific disease conditions to gain a deeper understanding of the underlying mechanisms of disease development. READ MORE

6. 9. Multivariate analyses of proteomic and metabolomic patterns in brain tumors

   Author : Carl Wibom; A Tommy Bergenheim; Henrik Antti; Mikael Johansson; Janne Lehtiö; Umeå universitet; []
   Keywords : glioblastoma; meningioma; proteomics; metabolomics; multivariate analyses; onkologi; Oncology;

   Abstract : Glioblastoma multiforme (GBM) is the most common primary brain tumor. Given the current standard of care, the prognosis for patients diagnosed with this disease is still poor. There consequently exists a need to improve current treatments, as well as to develop new ones. READ MORE

7. 10. Metabolomics studies of ALS : a multivariate search for clues about a devastating disease

   Author : Anna Wuolikainen; Peter M Andersen; Henrik Antti; Stefan L Marklund; Thomas Moritz; Thomas Hankemeier; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyotrophic lateral sclerosis ALS ; motor neuron disease; Lou Gehrig’s disease; human disease; CSF; biomarkers; metabolomics; metabonomics; chemometrics; design of experiments; multivariate analysis.; Neurology; Neurologi; Neurology; neurologi;

   Abstract : Amyotrophic lateral sclerosis (ALS), also known as Charcot’s disease, motor neuron disease (MND) and Lou Gehrig’s disease, is a deadly, adult-onset neurodegenerative disorder characterized by progressive loss of upper and lower motor neurons, resulting in evolving paresis of the linked muscles. ALS is defined by classical features of the disease, but may present as a wide spectrum of phenotypes. READ MORE