Search for dissertations about: "Henrik Nielsen"

Found 5 swedish dissertations containing the words Henrik Nielsen.

  2. 1. From Sequence to Sorting : Prediction of Signal Peptides

    Author : Henrik Nielsen; Philipp Bucher; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : In the present age of genome sequencing, a vast number of predicted genes are initially known only by their putative nucleotide sequence. The newly established field of bioinformatics is concerned with the computational prediction of structural and functional properties of genes and the proteins they encode, based on their nucleotide and amino acid sequences. READ MORE

  4. 2. Cell-penetrating peptides : Uptake mechanism and the role of receptors

    Author : Henrik Helmfors; Ülo Langel; Hanne Mørck Nielsen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Genes are the major regulators of biological processes in every living thing. Problems with gene regulation can cause serious problems for the organism; for example, most cancers have some kind of genetic component. Regulation of biological processes using oligonucleotides can potentially be a therapy for any ailment, not just cancer. READ MORE

  5. 3. Efficient Simulation and Optimal Control for Vehicle Propulsion

    Author : Anders Fröberg; Lars Nielsen; Karl-Henrik Johansson; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Automatic control; Reglerteknik;

    Abstract : Efficient drive cycle simulation of longitudinal vehicle propulsion models is an important aid for design and analysis of power trains. Tools on the market today mainly use two different methods for such simulations, forward dynamic or quasi-static inverse simulation. READ MORE

  6. 4. RNA-mediated gene expression regulation

    Author : Paula Petronela Groza; Francesca Aguilo; Yuri B. Schwartz; Silvia Remeseiro; Henrik Nielsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; fibrillarin; 2 -O-methylation; translation; alternative splicing; METTL3; m6A; ZFP207; breast cancer; mouse ESCs; molekylärbiologi; Molecular Biology;

    Abstract : The regulation of gene expression is a key mechanism that underlies all biological processes, from embryonic development to the onset and progression of various diseases, including cancer. A growing body of evidence places RNA molecules at the center of critical regulatory steps in gene expression. READ MORE

  7. 5. Pharmacometric Evaluation of Biomarkers to Improve Treatment in Oncology

    Author : Ida Netterberg; Lena Friberg; Mats Karlsson; Elisabet I. Nielsen; Henrik Lindman; Amit Roy; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; Biomarkers; Oncology; Population PKPD Modeling; NONMEM; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Cancer is a family of many different diseases with substantial heterogeneity also within the same cancer type. In the era of personalized medicine, it is desirable to identify an early response to treatment (i.e., a biomarker) that can predict the long-term outcome with respect to both safety and efficacy. READ MORE