Search for dissertations about: "Hep G2 cells"

Found 3 swedish dissertations containing the words Hep G2 cells.

  2. 1. The cytolethal distending toxin of Haemophilus ducreyi. Prevalence and effects on normal cells

    Author : Liselott Svensson; Göteborgs universitet; []
    Keywords : ;

    Abstract : Haemophilus ducreyi is a fastidious Gram-negative bacterium that causes the sexually transmitted disease chancroid. The disease is endemic in many developing countries and occurs as restricted outbreaks in the industrialised part of the world. READ MORE

  4. 2. Intoxication of mammalian cells by the cytolethal distending toxin of Haemophilus ducreyi : a novel mechanism of action

    Author : Ximena Cortes Bratti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The cytolethal distending toxins (CDTs) are a newly described family of bacterial protein toxins with a novel mechanism of action: DNA damage. Haemophilus ducreyi produces a cytotoxin that belongs to this family. This bacterium causes chancroid, a sexually transmitted disease, characterised by mucocutaneous, slowly healing genital ulcers. READ MORE

  5. 3. Studies on the transcriptional regulation of sterol 12alpha-hydroxylase (CYP8B1)

    Author : Yizeng Yang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acids; CYP8B1; CYP7A1; transcription; nuclear receptor; PPAR-alpha; HNF4-alpha; FTF; SREBP; thyroid hormones.;

    Abstract : The conversion of cholesterol into bile acids is mainly via two pathways, which are initiated by CYP7A1 and CYP27A1 respectedly. CYP8B1, a microsomal P450 cytochrome, hydroxylates of the steroid nucleus at the C-12alpha position to form 7alpha, 12alpha-dihydroxy-4-cholesten-3-one, a facultative precursor of CA. READ MORE