Search for dissertations about: "Hepatitis C virus"
Showing result 16 - 20 of 104 swedish dissertations containing the words Hepatitis C virus.
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16. On the outcome of antiviral therapy for hepatitis C virus genotype 2 or 3 infection
Abstract : Abstract Approximately 80% of patients infected with HCV genotypes 2 or 3 achieve a sustained virological response (SVR), following 24 weeks of therapy with ribavirin and pegylated interferon (peg-IFN), but in light of considerable side effects and cost, shortened treatment duration without impaired efficacy is desirable. Thus, 382 genotype 2/3 infected patients were randomized in an investigator-initiated phase III study (NORDynamIC) evaluating the efficacy of 12 (short-term) vs. READ MORE
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17. Epidemiology and clinical importance of GB virus C/hepatitis G virus
Abstract : GB virus C (GBV-C) or hepatitis G virus (HGV) is a recently discovered enveloped RNA virus belonging to the Flaviviridae family. GBV-C/HGV has been suggested to be a causative agent of non-A-non-E hepatitis. However, several contradictory observations cast doubts that it actually causes hepatitis. READ MORE
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18. Design and Synthesis of Acyclic and Macrocyclic Peptidomimetics as Inhibitors of the Hepatitis C Virus NS3 Protease
Abstract : Hepatitis C is a blood-borne disease affecting 130-170 million people worldwide. The causative agent, hepatitis C virus (HCV), infects the liver and is the major reason for chronic liver disease worldwide. The HCV NS3 protease, a key enzyme in the virus replication cycle, has been confirmed to be an important target for drug development. READ MORE
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19. Immunological and Genetic Markers Predicting Treatment Outcome in Hepatitits C Virus Infection
Abstract : Hepatitis C is a blood-borne infection caused by the hepatitis C virus (HCV). A chronic infection, which develops in most infected subjects, may lead to liver cirrhosis with ensuing liver dysfunction and liver cancer. READ MORE
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20. Posttransplant Lymphoproliferative Disorders : Studies of Epstein-Barr Virus, Regulatory T Cells and Tumor Origin
Abstract : Epstein-Barr virus (EBV) infects almost all humans and establishes lifelong latency in B cells. Posttransplant lymphoproliferative disorder (PTLD) is a rare but serious complication after transplantation triggered by immunosuppression and often related to EBV infection. READ MORE