Search for dissertations about: "Hepatocellular cancer"

Showing result 1 - 5 of 57 swedish dissertations containing the words Hepatocellular cancer.

2. 1. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics

   Author : Frida Ek; Mårten Fryknäs; Malin Jarvius; Rolf Larsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cancer cell quiescence; dormancy; three-dimensional; multicellular tumor spheroids; model development; cancer pharmacology; mitochondria; OXPHOS; colorectal carcinoma; hepatocellular carcinoma; Medicinsk vetenskap; Medical Science;

   Abstract : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. READ MORE

4. 2. Prognostic factors and tumor treatments in hepatocellular cancer

   Author : Malin Sternby Eilard; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatocellular cancer; prognostication;

   Abstract : Background: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death worldwide. Prognosis is related to tumor burden, liver function, and performance status as well as treatment factors. Accurate prognostication is a requisite for optimal treatment decisions. READ MORE

5. 3. Tumor-stroma interactions in hepatocellular carcinoma

   Author : Nataša Pavlović; Femke Heindryckx; Jessica Maiers; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatocellular carcinoma; fibrosis; endoplasmic reticulum stress; unfolded protein response; platelets; P2Y12; Molekylär cellbiologi; Molecular Cellbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Abstract : Hepatocellular carcinoma (HCC), a highly deadly primary liver cancer with a rising global incidence and limited therapeutic options, is characterized by a vicious cross-talk between the tumor and its surrounding hepatic stroma. The stromal environment, consisting of hepatic stellate cells (HSC), endothelial cells, resident and infiltrating macrophages and other immune cells, platelets and extracellular matrix (ECM) components, actively contributes to creating an ideal niche for tumor proliferation and invasiveness. READ MORE

6. 4. The importance of Cyclophilins and Mps1 in cancer

   Author : Sonia Simon Serrano; Klinisk neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclophilins; liver; fibrosis; HCC; cell cycle; Mps1 and mitosis;

   Abstract : Hepatic fibrosis is a pathological response to chronic liver injuries such as chronic alcohol consumption, non-alcoholic fatty liver disease (NAFLD) or chronic viral infections. No antifibrotic compound has been approved for liver fibrosis and if the cause of the chronic injury is not solved, fibrosis can progress to cirrhosis. READ MORE

7. 5. Enteric Helicobacter and H. pylori in chronic inflammation and cancer of the hepatobiliary tract and pancreas

   Author : Hans-Olof Nilsson; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mykologi; virology; bacteriology; Microbiology; hepatocellular cancer; Helicobacter; PCR-denaturing gradient gel electrophoresis; oncology; cancerology; Cytologi; onkologi; cancer; mycology; bakteriologi; virologi; Cytology;

   Abstract : The Helicobacter genus now consists of at least 26 species, with additional novel species in the process of being validated. Beyond the impact of H. READ MORE