Search for dissertations about: "Herpes Simplex"

Showing result 1 - 5 of 80 swedish dissertations containing the words Herpes Simplex.

  1. 1. Herpes simplex ribonucleotide reductase

    Author : Rolf Ingemarson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Ribonucleotide reductase; herpes simplex virus;

    Abstract : In all bacterial, plant and animal cells, as well as in many viruses, genetic information resides in DNA (deoxyribonucleic acid). Replication of DNA is essential for proliferation, and DNA-containing viruses (such as herpesviruses) must carry out this process within the mammalian cells they infect. READ MORE

  2. 2. Initiation of herpes simplex virus DNA replication

    Author : Stina Simonsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; initiation of DNA replication; origin binding protein; Herpes Simplex Virus;

    Abstract : During virus infection multiple new copies of the virus genome are made by a DNA synthesis machinery. Initiation of DNA replication involves the recognition of origins of DNA replication by an initiator protein. READ MORE

  3. 3. Herpes simplex virus infection: epidemiological aspects and analysis of the type-specific antibody response

    Author : Petra Tunbäck; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpes simplex virus; first episode genital herpes; seroepidemiology type-specific antibody-response; glycoprotein G-1; epitope-mapping;

    Abstract : Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are ubiquitous viruses, often leading to asymptomatic infections in humans. However, different clinical presentations can be seen including recurrent oral or genital lesions, meningitis and neonatal herpes. READ MORE

  4. 4. Activation of Herpes simplex virus type 1 origin of DNA replication

    Author : Alireza Aslani; Göteborgs universitet; []
    Keywords : DNA replication; Herpes simplex virus; helicase; UL9; OBP; ICP8; ATP; oriS; hairpin;

    Abstract : Herpes simplex virus type 1 has been used to study the molecular mechanism of DNA replication. Initiation of DNA replication takes place at specific regions called origins of replication. The HSV-1 genome contains three origins of replication, one copy of oriL and two copies of oriS. READ MORE

  5. 5. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products

    Author : Mårten Strand; Göran Wadell; Mikael Elofsson; Ya-Fang Mei; Lieve Naesens; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virology; antiviral; adenovirus; herpes simplex virus; small molecule; inhibitor; hsv; drug discovery; medicinsk virologi; Medical Virology; datorlingvistik; computational linguistics; mikrobiologi; Microbiology;

    Abstract : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. READ MORE