Search for dissertations about: "Hippo"

Showing result 1 - 5 of 15 swedish dissertations containing the word Hippo.

  2. 1. Genetic modeling of the Hippo pathway in hematopoietic stem cells

    Author : Lina Jansson; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cells; hematopoiesis; Hippo pathway; hematopoietic stem cells;

    Abstract : Hematopoiesis is the process of blood formation from a limited pool of hematopoietic stem cells (HSCs). These rare stem cells can both self-renew to maintain the HSC pool, and differentiate to continuously replenish lost blood cells. The mechanisms of HSC regulation are not fully known. READ MORE

  4. 2. Analysis of signaling pathway activity in single cells using the in situ Proximity Ligation Assay

    Author : Linda Arngården; Ola Söderberg; Niclas Karlsson; Uppsala universitet; []
    Keywords : cell signaling; Wnt; Hippo; TGFB; Molekylär medicin; Molecular Medicine;

    Abstract : A cell that senses signals from its environment uses proteins for signal transduction via post translational modifications (PTMs) and protein- protein interactions (PPIs) from cell membrane into the nucleus where genes controlling cell proliferation, differentiation and apoptosis can be turned on or off, i.e. READ MORE

  5. 3. Role of the co-transcriptional regulators Yap/Taz in the normal and fibrotic lung epithelia

    Author : Hani N. Alsafadi; NanoLund: Centre for Nanoscience; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung Epithelium; idiopathic pulmonary fibrosis IPF ; Developmental pathways; Hippo Signaling; Yap Taz; transcription factors; 3D culture models; ;

    Abstract : Idiopathic pulmonary fibrosis (IPF) is a fatal disease that exhibits patterns of usual interstitial pneumonia with honeycombing. IPF is characterized by damaged distal lung epithelium with excessive tissue scarring and extracellular matrix remodeling. The etiology of IPF is unknown and current therapies cannot end or reverse disease progression. READ MORE

  6. 4. From environmental cue to phenotypic variation – a functional investigation of wing polyphenism in an emerging model species

    Author : Erik Gudmunds; Arild Husby; Laura C. Lavine; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Gerris buenoi; water strider; wing polyphenism; photoperiodism; Fat Hippo signaling; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Phenotypic plasticity is a ubiquitous feature of living organisms and enable individuals to adapt to changing environments. A particularly prominent example of plasticity is found in polyphenisms, where environmental cues received during development leads to the generation of discrete variation in populations. READ MORE

  7. 5. De musica liber VI / Aurelius Augustinus : A critical edition with a translation and an introduction

    Author : Martin Jacobsson; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; Augustine of Hippo; Late Antique philosophy and theology; artes liberales; De musica; numeri rhythms ; relation between body and soul; sense perception; unitas; the ordering of the universe; contemplation of God; Deus creator omnium; Latin; latin;

    Abstract : Around the time of his famous conversion in 386, Augustine planned to dedicate a treatise to each of the artes liberales. However, he finished only a work on grammar and the first part of the De musica (books I-VI), which deals with rhythmus\the second part, which was to treat melos, was never written, since Augustine became occupied with his ecclesiastical career. READ MORE