Search for dissertations about: "Histo-blood group antigens"

Showing result 6 - 10 of 15 swedish dissertations containing the words Histo-blood group antigens.

2. 6. Computational analysis of oligosaccharide conformations – methodological development, applied studies, and design of glycomimetics

   Author : Francesco Strino; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; histo-blood group antigens; Burkholderia cepacia; genetic algorithms; norovirus; selenoglycosides; sugar conformations; thioglycosides; saccharide conformations;

   Abstract : Carbohydrates are the most abundant class of biomolecules. Besides their roles as structural elements and energy storage, they are involved in signaling and recognition processes. Their functions and activities depend on their preferred conformations. READ MORE

4. 7. Gastrointestinal norovirus infections and the development of the next generation of mucosal vaccines

   Author : Inga Rimkute; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human norovirus; gastrointestinal infection; mucosal vaccine; subcomponent vaccine; human intestinal enteroids; histo-blood group antigens; lipidomics; glycoproteomics; glycosphingolipids;

   Abstract : Human norovirus (HuNoV) is the causative agent of the winter vomiting disease and the leading cause of outbreaks of gastrointestinal infections across all settings and age groups in the world. The virus is highly contagious making outbreaks difficult or often impossible to control and having a high impact on societal costs and resources. READ MORE

5. 8. Probing and elucidating the dynamics of virus-membrane interaction via plasma membrane mimics

   Author : Konrad Thorsteinsson; Marta Bally; Hudson Pace; Gisa Gerold; Susan Daniel; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; supported lipid bilayer; binding kinetics; equilibrium fluctuation analysis; TIRF; FRET; norovirus; HSV; SARS-CoV-2; histo-blood group antigens; ApoE; heparan sulfate; mikrobiologi; Microbiology;

   Abstract : Virus infection is initiated by the attachment of a virion to a susceptible cell’s plasma membrane, in a highly dynamic and well-orchestrated process that encompasses various steps and engages numerous viral and cellular factors. These dynamic steps may include initial non-specific binding to ubiquitous cell-membrane ligands, diffusion across the membrane to a suitable entry site and virus engagement with various receptors and co-receptors on the cell surface. READ MORE

6. 9. Chemical basis of ABO subgroups

   Author : Lola Svensson; Göteborgs universitet; []
   Keywords : ABO; subgroups; glycolipid; para-Forssman; Forssman; Forssman synthetase;

   Abstract : Despite the ABO histo-blood group system being the most biologically significant in humans the chemical structures that define its various phenotypes still remain largely unresolved. Like all blood group systems there is a significant range in the amount of antigen present on the red cells of an individual and there exists a range of so-called “weak” phenotypes represented by decreasing expression of A or B antigens. READ MORE

7. 10. Evaluation of fucosylated receptors for Cholera toxin in the human small intestine

   Author : Jakob Cervin; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cholera toxin; Lewis antigen; HBGA; HMO; Fucose; GM1;

   Abstract : Cholera toxin (CT) produced by Vibrio cholerae is the causative agent for the diarrheal disease cholera. Cholera is yearly afflicting millions and is estimated to kill over 100 000 people every year. In this thesis I aimed to better understand the role of noncanonical CT receptors, e.g. READ MORE