Search for dissertations about: "Histone deacetylase inhibitor"
Showing result 16 - 20 of 24 swedish dissertations containing the words Histone deacetylase inhibitor.
-
16. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer
Abstract : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. READ MORE
-
17. Redox alterations in inflammatory diseases : diabetes, kidney failure and cancer
Abstract : In order to combat oxidative stress and maintain the intracellular redox homeostasis, cells are equipped with antioxidant systems. The thioredoxin and glutaredoxin systems are the major thiol reducing systems and central antioxidant systems in mammalian cells. READ MORE
-
18. Patterning during embryo development in Pinus : with special emphasis on somatic embryogenesis in Scots pine (Pinus sylvestris L.)
Abstract : Somatic embryogenesis is an attractive method to propagate conifers vegetatively. However, many species belonging to Pinus are recalcitrant to somatic embryo development. The overall aim of this thesis has been to gain a better understanding of the developmental pathway leading to cotyledonary somatic embryos of Scots pine (Pinus sylvestris). READ MORE
-
19. Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment
Abstract : Background: Pancreatic cancer is the fourth leading cause of cancer-related death. Only about 6% of patients are alive 5 years after diagnosis. One reason for this low survival rate is that most patients are diagnosed at a late stage, when the tumor has spread to surrounding tissues or distant organs. READ MORE
-
20. Epigenetics in nasopharyngeal carcinoma
Abstract : Nasopharyngeal carcinoma (NPC) shows a remarkably distinctive ethnic and geographic distribution among the world suggesting that genetic susceptibility backgrounds cooperate with the environmental risk factors in etiology of NPCs. Among the environmental factors, much attention has been focused on a well-documented association with Epstein-Barr virus (EBV), which can be detected in 100% undifferentiated NPCs. READ MORE