Search for dissertations about: "Histone"

Showing result 1 - 5 of 229 swedish dissertations containing the word Histone.

  1. 1. Histone H1 Subtypes and phosphorylation in cell life and death

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Anna Gréen; Linköpings universitet.; Linköpings universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi;

    Abstract : The genetic information of a human diploid cell is contained within approximately 2 metres of linear DNA. The DNA molecules are compacted and organized in various ways to fit inside the cell nucleus. Various kinds of histones are involved in this compaction. One of these histones, histone H1 is the topic of the present thesis. READ MORE

  2. 2. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression

    University dissertation from Umeå : Umeå University

    Author : Eshagh Dorafshan Esfahani; Umeå universitet.; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Trithorax Group proteins; Polycomb Group proteins; PRC1; PRC2; PRE; histone methylation; histone ubiquitylation; Ash1; SET domain; H3K36; H3K27; Drosophila;

    Abstract : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. READ MORE

  3. 3. The release of histone proteins from cells via extracellular vesicles

    University dissertation from Umeå : Umeå University

    Author : Uma Muthukrishnan; Umeå universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

    Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE

  4. 4. Clinical management of pancreatic cancer aided by histone signatures

    University dissertation from Lund University, Faculty of Medicine

    Author : Monika Bauden; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic cancer; Histone modifications; Tumor size; Biomarkers; Tumor; LC MS MS; Nucleosomics; Histone H1.3;

    Abstract : .... READ MORE

  5. 5. Chromatin, histones, and epigenetic tags

    University dissertation from Institutionen för biomedicin och kirurgi

    Author : Elisavet Koutzamani; Linköpings universitet.; Linköpings universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chromatin; histones; histone variants; epigenetics; histone H4 methylation; linker histone phosphorylation; MEDICINE Morphology; cell biology; pathology Cell biology Medical cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi Medicinsk cellbiologi;

    Abstract : The fundamental building blocks of chromatin are the nucleosomes. Each such unit is composed of about 200 bp of DNA, the well-conserved core histones (H2A, H2B, H3 and H4) and a linker histone (H1). READ MORE