Search for dissertations about: "History of genetics"

Showing result 1 - 5 of 148 swedish dissertations containing the words History of genetics.

  2. 1. Archaeological Genetics - Approaching Human History through DNA Analysis

    Author : Evangelia Daskalaki; Anders Götherström; Mattias Jakobsson; Walther Parson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ancient DNA; pyrosequencing; molecular genetics; aDNA; neolithization; evolutionary genetics; mtDNA; viking age; archaeological genetics; genetik; evolutionsgenetik; naturvetenskap; neolitisering; vikingatid; arkeologisk genetik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : There are a variety of archaeological questions, which are difficult to assess by traditional archaeological methods. Similarly, there are genetic and population genetic questions about human evolution and migration that are difficult to assess by studying modern day genetic variation. READ MORE

  4. 2. Population Genetics of Human Genomic Elements

    Author : Thijessen Naidoo; Mattias Jakobsson; Guillaume Achaz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; population genetics; human genome; functional elements; natural selection; pseudogenes; loss-of-function; gene regulation; Y chromosome; Biology with Specialisation in Human Evolution and Genetics; Biologi med inriktning mot människans evolution och genetik;

    Abstract : The genomes of living organisms are composed of a multitude of functional units, which interact with each other and their environment in a highly regulated fashion, to facilitate the expression of an enduring (and evolving) phenotype. Several approaches have emerged in the effort to identify these functional units and explore their activities. READ MORE

  5. 3. Exploring the Genetics of SLE with Linkage and Association Analysis

    Author : Cecilia Johansson; Marta Alarcón-Riquelme; Peter Gregersen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Systemic lupus erythematosus; complex disease; linkage analysis; association analysis; Genetik; Genetics; Genetik;

    Abstract : The aim with this thesis has been to identify genes involved in the pathogenesis of Systemic Lupus Erythematosus (SLE). SLE is a systemic autoimmune disorder, most likely caused by both several genetic and environmental factors. READ MORE

  6. 4. Postglacial Population History of the Common Shrew (Sorex araneus) in Fennoscandia : Molekylära studier av återkolonisation, könsbundet genflöde och kromosomrasbildning

    Author : Anna-Carin Andersson; Håkan Tegelström; Cecilia Alström-Rapaport; Jeremy B Searle; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Sorex araneus; chromosome race; postglacial recolonisation; hybrid zone; sex-biased gene flow; chromosomal evolution; Genetik; Genetics; Genetik;

    Abstract : The common shrew, Sorex araneus, has one of the most variable karyotypes among mammals, displaying numerous chromosomes races throughout its distribution, which can be categorized into different karyotypic groups. The objective of this thesis was to examine the postglacial population history of Fennoscandian common shrews using autosomal microsatellites, mitochondrial DNA (mtDNA) and a Y chromosome specific microsatellite (L8Y). READ MORE

  7. 5. The Effects of Mutation and Selection on the Rate and Pattern of Molecular Evolution in Birds

    Author : Sofia Berlin; Hans Ellegren; Adam Eyre-Walker; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; substitution rate; diversity; selection; male mutation bias; birds; Genetik; Genetics; Genetik;

    Abstract : By comparing sequence diversity and divergence on sex chromosomes one can study how the rate of evolution in affected by mutation and/or selection. The rate of mutation in male biased, meaning that relatively more mutations are created in the male germ line than in the female. READ MORE