Search for dissertations about: "Hjalmar Brismar"
Showing result 1 - 5 of 23 swedish dissertations containing the words Hjalmar Brismar.
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1. The Biophysics of Na+,K+-ATPase in neuronal health and disease
Abstract : Na+,K+-ATPase is one of the most important proteins in the mammalian cell. It creates sodium and potassium gradients which are fundamental for the membrane potential and sodium-dependent secondary active transport. READ MORE
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2. Photophysical and Chemical Approaches to Cellular Biophysics
Abstract : The central theme in this thesis is reversibility. Two main attempts has been made to approach reversibility in cellular systems from both chemical and physical points of view. READ MORE
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3. Quantitative bioimaging in single cell signaling
Abstract : Imaging of cellular samples has for several hundred years been a way for scientists to investigate biological systems. With the discovery of immunofluorescence labeling in the 1940’s and later genetic fluorescent protein labeling in the 1980’s the most important part in imaging, contrast and specificity, was drastically improved. READ MORE
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4. Advancing tissue clearing and expansion methods for high-resolution volumetric imaging of biological samples
Abstract : The development of advanced light microscopes, capable of imaging samples at ever-higher spatial resolution and increasing speeds is an ongoing endeavour. The sample itself is an integral part of the microscope and, unlike the intricately positioned and highly polished lenses, it is an optically unpredictable component. READ MORE
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5. Functional association networks for disease gene prediction
Abstract : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. READ MORE