Search for dissertations about: "Hodgkin’s lymphoma"

Showing result 11 - 15 of 48 swedish dissertations containing the words Hodgkin’s lymphoma.

  1. 11. Mechanisms of immune escape in EBV associated malignancies : Hodgkin's disease and Burkitt's lymphoma

    Author : Teresa Frisan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Epstein-Barr virus; tumor immune escape; antigen presentation; cytotoxic T lymphocytes;

    Abstract : The work presented in this thesis is focused on the analysis of the mechanisms operating in the immune escape of two Epstein-Barr virus (EBV) associated tumors: Hodgkin's Disease (HD) and Burkitt's lymphoma (BL). EBV positive HD tumor cells express at least 3 viral proteins: the EBV nuclear antigen (EBNA)1, the latent membrane proteins (LMP)1 and LMP2A. READ MORE

  2. 12. Computed tomography, magnetic resonance imaging and positron emission tomography in non-Hodgkin's lymphoma

    Author : Miriam Rodriguez; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; NHL; CT; MRI; PET; malignancy grade; prognosis; residual mass; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

    Abstract : Certain aspects of the use of computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) were evaluated in patients with non-Hodgkin'slymphoma (NHL) with the aim of improving the management of these patients.Subjective evaluation of the tumor pattern on CT images, and quantification of tracer uptake using 11C methionine (11C Met) and [18F] fluorodeoxyglucose (18FDG) PET in patients with NHL, were performed to determine their relations to malignancy grade. READ MORE

  3. 13. Hepatitis C virus infection : a nationwide study of associated morbidity and mortality

    Author : Ann-Sofi Duberg; Erik Bäck; Karl Ekdahl; Rolf Hultcrantz; Anders Blaxhult; Johan Carlson; Örebro universitet; []
    Keywords : HCV; hepatitis C; epidemiology; non-Hodgkin s lymphoma; NHL; multiple myeloma; primary liver cancer; HCC; mortality; inpatient care; hospitalization; MEDICINE; MEDICIN; Infektionssjukdomar; Infectious Diseases; Epidemiology; Epidemiologi; Medicin; Medicine;

    Abstract : The hepatitis C virus (HCV) was characterised in 1989. HCV was transmitted through transfusion of blood/blood products, but injection drug use is now the most common route of transmission. READ MORE

  4. 14. Tumor-targeted superantigens for experimental immunotherapy of human leukemia/lymphoma

    Author : Cecilia Weigelt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; SAg; SEA; SEAm; HLA class II; TCR; CFL; SDCC; cytotoxicity; TNF a; IFN g; mAb; PA-SEAm; anti-CD19-Fab-SEAm; B-CLL; B-NHL; AML; CML; immunotherapy; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

    Abstract : Bacterial superantigens (SAgs) have the property of stimulating high proportions of T cells expressing certain TCR Vβ sequences. The SAg first binds with high affinity to HLA class II molecules on the target cell and then stimulates the T cell to produce cytokines and to become cytotoxic. READ MORE

  5. 15. Regulation of molecular processes in diffuse large B-cell lymphoma

    Author : Therese Högfeldt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The molecular understanding of diseases has advanced rapidly due to the use of gene expression profiling. However, these methods have been hampered by the limitation to use frozen tissue specimens. Formalin fixation and paraffin embedding (FFPE) is a standard procedure for long time storage of tissues. READ MORE