Search for dissertations about: "Homo sapiens"

Showing result 1 - 5 of 11 swedish dissertations containing the words Homo sapiens.

  1. 1. Nucleotide Binding to Trimeric dUTPase: Studies on Recombinant Enzymes using Kinetic and Spectroscopic Methods

    Author : Johan Nord; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; C-terminus; dUTPase; EIAV; Escherichia coli; flexibility; Homo sapiens; kinetics; NMR; nucleotide metabolism; rate constants of lig-and binding; production of recombinant enzyme; dUTP; specificity; Biochemistry; Metabolism; Biokemi;

    Abstract : Recombinant dUTPase from the bacterium Escherichia coli, the retrovirus equine infectious anemia virus (EIAV) and Homo sapiens have been made available for physico-chemical characterisation. The protocols developed have also proven to be suitable for production of enzymes modified by isotope labelling or other methods. READ MORE

  2. 2. Exploring the steroidogenic activity of glutathione transferases across species

    Author : Helena Lindström; Bengt Mannervik; Kjell Wikvall; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glutathione transferase; steroidogenesis; GST A3-3; testis; androstenedione; pregnenedione; equine; steroidogenesis inhibition; Drosophila GSTE14; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication. However, some GSTs have developed alternative functions. READ MORE

  3. 3. Equine glutathione transferase A3-3 : an efficient steroid isomerase

    Author : Helena Lindström; Bengt Mannervik; Ann-Kristin Östlund Farrants; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Equine; glutatione transferase; steroidogenesis; steroid isomerase; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication by making toxic electrophiles more polar and therefore more easily excretable. However some GSTs have developed alternative functions. READ MORE

  4. 4. Computational Approaches to the Identification and Characterization of Non-Coding RNA Genes

    Author : Pontus Larsson; Anders Virtanen; Leif Kirsebom; Stephen Mount; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ncRNA; snRNA; U1; splice site; alternative splicing; Dictyostelium; nucleotide composition; partial sums; Bioinformatics; Bioinformatik;

    Abstract : Non-coding RNAs (ncRNAs) have emerged as highly diverse and powerful key players in the cell, the range of capabilities spanning from catalyzing essential processes in all living organisms, e.g. protein synthesis, to being highly specific regulators of gene expression. READ MORE

  5. 5. The transaldolase family : structure, function and evolution

    Author : Stina Thorell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The transaldolase gene family includes representatives from all kingdoms of life and the encoded enzymes are important for carbohydrate metabolism. The family can be divided into two subfamilies; Classical transaldolases and the MipB/TalC proteins. READ MORE