Search for dissertations about: "Hormone Antagonists"

Showing result 1 - 5 of 20 swedish dissertations containing the words Hormone Antagonists.

  2. 1. Identification and evaluation of growth hormone antagonists

    Author : Linda Rosengren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : States in which Growth hormone (GH) levels are elevated have been implicated in several physiological disorders such as acromegaly, diabetic complications and progression of malignancies. Classical treatments for acromegaly are surgery and radiotherapy but also pharmacological therapies exist. READ MORE

  4. 2. Interaction of Xenobiotics with the Glucocorticoid Hormone System in vitro

    Author : Maria Johansson; Helen Håkansson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; DDT; PCB; tolylfluanid; adrenal; CYP11B1; glucocorticoid receptor; endocrine disrupter; Biologi; Biology; Biologi; Ecotoxicology; ekotoxikologi;

    Abstract : Persistent environmental pollutants were examined for their interaction with the glucocorticoid hormone system. The focus was placed on interference with the glucocorticoid synthesis and the glucocorticoid-signalling pathway in various in vitro test systems. READ MORE

  5. 3. Regulation of apoptosis and steroidogenesis in ovarian preovulatory granulosa cells

    Author : Eva Svensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; granulosa cells; luteinizing hormone; progesterone receptor; RU 486; Org 31710; leptin; steroidogenesis;

    Abstract : Only a minute fraction of ovarian follicles present in a foetal ovary will complete the path to ovulation. The majority of the follicles will instead undergo atresia, a hormonally controlled apoptotic process. Apoptosis occurs throughout follicle development, with an extensive reduction in the number of follicles present at birth. READ MORE

  6. 4. The Gastrin-ECL Cell Axis. Functional Aspects

    Author : Maria Björkqvist; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Pharmacological sciences; Calcium channels; CCK receptor antagonists; Misoprostol; Galanin; Somatostatin; Pancreastatin; Histamine; VIP; Gastrin; PACAP;

    Abstract : The ECL cells constitute a prominent endocrine cell population in the acid-producing part of the stomach. They are controlled by circulating gastrin released from G-cells in the antrum. In response to gastrin, they secrete histamine, that in turn stimulates the parietal cell to secrete acid. READ MORE

  7. 5. Rheumatoid arthritis : pharmacological modulation of cytokines : aspects of clinical response and endocrine regulation

    Author : Sofia Ernestam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Rheumatoid arthritis; cytokines; gold sodium thiomalate; TNF-antagonists;

    Abstract : Rheumatoid arthritis (RA) is a systemic inflammatory disease primarily affecting the joints. In the pathogenesis several cells of the immune systeme and messengers of the immune systeme, cytokines, are important. READ MORE