Search for dissertations about: "Host-virus interaction"
Showing result 1 - 5 of 6 swedish dissertations containing the words Host-virus interaction.
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1. Host-Virus Interactions in Asthma and COPD
Abstract : Asthma and chronic obstructive pulmonary disease (COPD) are associated with periods of worsened symptoms, known as exacerbations. Severe exac-erbations can result in hospitalisation, irreversible decline of the disease and sometimes death. Thus, exacerbations are a major cause of morbidity, mortality and healthcare cost. READ MORE
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2. Exploration of analytical methods to study motif-mediated host-virus protein-protein interactions
Abstract : Proteins are responsible for countless processes in living creatures, but most often they do not perform these tasks alone. Rather, they engage in interactions with other proteins, creating whole protein-protein interaction (PPI) networks. READ MORE
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3. Global Profiling of Host Cell Gene Expression During Adenovirus Infection
Abstract : To investigate mechanisms involved in virus-host interactions, global changes in host gene expression were examined during infection with adenovirus type 2 (Ad2) using cDNA microarray technology. In paper I and II, transcriptional changes in HeLa cells were investigated during the early and late phase of infection, respectively. READ MORE
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4. Analysis of PDGF receptor internalization and signaling using proximity ligation assays
Abstract : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. READ MORE
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5. Viruses on the wing : evolution and dynamics of influenza A virus in the Mallard reservoir
Abstract : This thesis explores the evolution of avian influenza A viruses (IAV), as well as host-pathogen interactions between these viruses and their main reservoir host, the Mallard (Anas platyrhynchos). IAV is a genetically diverse, multi-host virus and wild birds, particularly dabbling ducks, are the natural reservoir. READ MORE