Search for dissertations about: "Huan"

Showing result 1 - 5 of 14 swedish dissertations containing the word Huan.

  1. 1. A multi-omics approach to uncover estrogen receptor (ER) and activator protein 1 (AP-1) signaling networks in breast cancer

    Author : Huan He; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Estrogen receptor (ER) binds to DNA indirectly through other transcription factors (e.g. AP-1) to modulate gene expression, which is a tethering mechanism. The ER/AP-1 crosstalk plays an important role in tamoxifen therapy resistance. READ MORE

  2. 2. Ab initio driven modeling of advanced nuclear fuels

    Author : Huan Liu; Pär Olsson; Marjorie Bertolus; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysik; Physics; Kärnenergiteknik; Nuclear Engineering;

    Abstract : With the development of clean energy sources such as nuclear power, it has become more important to use advanced nuclear fuels to improve economic efficiency and expand safety margins. Thanks to the high fissile density, high thermal conductivity, and high melting point, uranium nitride and uranium silicide have been considered accident tolerant or high-performance fuels for commercial light water reactors and for future generation reactor systems. READ MORE

  3. 3. Aldolases for Enzymatic Carboligation : Directed Evolution and Enzyme Structure-Function Relationship Studies

    Author : Huan Ma; Mikael Widersten; Wolf-Dieter Fessner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aldolase; 2-deoxyribose-5-phosphate aldolase; fructose-6-phosphate aldolase; directed evolution; enzyme dynamics; Biokemi; Biochemistry;

    Abstract : The research summarized in this thesis focuses on directed evolution and enzyme mechanism studies of two aldolases: 2-deoxyribose-5-phosphate aldolase (DERA) and fructose-6-phosphate aldolase (FSA).Aldolases are nature’s own catalysts for one of the most fundamental reactions in organic chemistry: the formation of new carbon-carbon bonds. READ MORE

  4. 4. Changes of stomach microenvironment and gastric cancer development

    Author : Huan Song; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : While acknowledging the importance of microenvironment-related events, e.g. Helicobacter pylori (H. READ MORE

  5. 5. Towards quinone/pEDOT conducting redox polymers as energy storage materials

    Author : Huan Wang; Martin Sjödin; Xavier Crispin; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; quinone; conducting redox polymer; doping; capacity; organic battery; polymerization;

    Abstract : With the increased demand for electrical energy storage devices, e.g. electric vehicles and smart grids, organic batteries have caught increasing attention due to their advantages, such as sustainability, environmental friendliness and cheap raw materials over traditional inorganic energy storage materials. READ MORE