Search for dissertations about: "Hulda Hreggvidsdottir"

Found 1 swedish dissertation containing the words Hulda Hreggvidsdottir.

2. 1. Dual cytokine inducing properties of HMGB1

   Author : Hulda Hreggvidsdottir; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : High mobility group box protein 1 (HMGB1) is a nuclear protein that can be released either passively by necrotic cells or actively by stimulated cells. Extracellular HMGB1 is a potent inducer of inflammation and the importance of HMGB1 as a mediator in a number of inflammatory diseases including rheumatoid arthritis, sepsis and ischemia‐reperfusion injury, has been demonstrated by successfully targeting the protein in preclinical models. READ MORE