Search for dissertations about: "Human C4b-binding protein"

Showing result 11 - 15 of 16 swedish dissertations containing the words Human C4b-binding protein.

  2. 11. MORAXELLA CATARRHALIS OUTER MEMBRANE PROTEINS AND INTERACTIONS WITH THE HUMAN IMMUNE SYSTEM

    Author : Therése Nordström; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; Mikrobiologi; virology; Microbiology; C4BP; B-cells; UspA2; Moraxella catarrhalis; virologi; mykologi; bakteriologi; bacteriology; C3; IgD; Moraxella IgD-bindning protein; UspA1;

    Abstract : Moraxella catarrhalis is frequently colonizing the human respiratory tract, particularly in children. This gram-negative bacterium has during the last two decades been recognized as a pathogen causing otitis media in children and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). READ MORE

  4. 12. Interactions between streptococcal M proteins and human plasma proteins

    Author : Charlotta Sandin; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; innate immunity; Streptococcus pyogenes; phagocytosis resistance;

    Abstract : Streptococcus pyogenes is a common human pathogen, which causes a variety of diseases. A major virulence factor of S. pyogenes is the surface-associated M protein, which mediates resistance to phagocytosis. Several studies indicate that M proteins inhibit complement deposition and thereby phagocytosis. READ MORE

  5. 13. Complement evasion strategies of human pathogens - the evolutionary arms race

    Author : Monika Jusko; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system; pathogen; periodontitis; proteases; immune escape;

    Abstract : Although the complement system, a pivotal component of innate immunty, is centrally involved in host defense against pathogens, its overactivation or deregulation may excessively amplify inflammation and contribute to immunopathology. Periodontitis, an oral infection-driven chronic inflammatory disease, has been linked with complement disruption by periodontal bacteria, resulting in inflammation and pathogenesis. READ MORE

  6. 14. Molecular and cellular mechanisms during adherence and cell signaling of pathogenic Neisseria to host cells

    Author : Helena Källström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neisseria; pili; adhesion; PiIC; CD46; signaling; G-protein;

    Abstract : The pathogenic members of the genus Neisseria include N. gonorrhoeae and N. meningitidis. Both organisms are obligate human pathogens that colonize mucosal surfaces. READ MORE

  7. 15. Molecular studies of Neisseria : host cell interactions

    Author : Anne Rytkönen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Neisseria family includes many non-pathogenic species but also two strict human pathogens; Neisseria gonorrhoeae and Neisseria meningitidis. Both organisms colonise mucosal surfaces and may cause disseminated infections upon passage of the epithelial barrier. READ MORE