Search for dissertations about: "Human Embryonic Kidney cells"

Showing result 1 - 5 of 21 swedish dissertations containing the words Human Embryonic Kidney cells.

  2. 1. Embryonic Stem Cells: Differentiation into Insulin Producing Cells and Elimination of Damaged Proteins

    Author : Gabriella Brolén; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; oxidatively damaged proteins; diabetes; carbonyl; C-peptide; Medicine human and vertebrates ; insulin; human embryonic stem cell; 20S proteasome; AGE; Pdx1; proinsulin;

    Abstract : This thesis includes two different parts: One focusing on how to induce human embryonic stem cells (hESCs) to differentiate into insulin producing cells by following the normal pancreatic development pathway. These cells have then the potential to be an unlimited source for diabetes regenerative medicine. READ MORE

  4. 2. Hydrodynamics considerations in cells systems from ocean flow to perfusion cultivation process

    Author : Caijuan Zhan; Véronique Chotteau; Jeffrey Chalmers; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microorganism; cells; hydrodynamics; turbulence; numerical simulation; CFD; Resonance; Wave bioreactor; ATF; TFF; perfusion; design feeding strategy; Bioteknologi; Biotechnology;

    Abstract : Microorganisms and animal cells are grown surrounded by fluid, which is providing them with nutrients and removing their waste products. In nature and industry processes, cells/microbes can be subject to aggressive environments, such as turbulent flow or shear flow. READ MORE

  5. 3. Tools for the development of intensified perfusion processes for mammalian cell culture

    Author : Hubert Schwarz; Véronique Chotteau; Mark Smales; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Recombinant protein biomanufacturing; Perfusion process; Integrated continuous bioprocessing; Monoclonal antibody; Erythropoietin; Chinese Hamster Ovary cells; Human Embryonic Kidney cells; Perfusion medium optimization; Cell specific perfusion rate; Raman spectroscopy; N-glycosylation; Microbioreactors; Design of Experiments; Biotechnology; Bioteknologi;

    Abstract : Recombinant protein therapeutics have become an indispensable part of modern medicine to treat a wide variety of diseases. Their manufacture is mostly based on mammalian cells with fed-batch production bioreactors and downstream batch purification unit operations. READ MORE

  6. 4. The importance of Foxi1 expression in kidney and inner ear

    Author : Sandra Rodrigo Blomqvist; Göteborgs universitet; []
    Keywords : Foxi1; intercalated cells; endolymphatic sac; acid base regulation;

    Abstract : The forkhead (FOX) genes comprise a family of transcription factors involved in generegulation in both embryonic and adult tissue. Foxi1 is expressed in the kidney andthe developing inner ear. We examined the significance of Foxi1 in these two organsand explain the molecular mechanisms behind the phenotype seen in Foxi1 deficientmice. READ MORE

  7. 5. Transcriptional profiling of the kidney glomerulus

    Author : Ying Sun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The kidney glomerulus plays a crucial role in ultraltration of the blood through the glomerular capillary wall. Glomerulus injury may occur in many systemic and primary kidney diseases or as secondary eects to drugs and infections. READ MORE