Search for dissertations about: "Human proteome"

Showing result 11 - 15 of 141 swedish dissertations containing the words Human proteome.

  2. 11. Towards subcellular localization of the human proteome using bioimaging

    Author : Charlotte Stadler; Emma Lundberg; Carolina Wählby; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibody; antibody validation; automated image analysis; automated microscopy; cell line; confocal microscopy; fixation; green fluorescent protein GFP ; immunofluorescence IF ; organelle; protein expression; siRNA; subcellular localization;

    Abstract : Since the publication of the complete sequence of the human genome in 2003 there has been great interest in exploring the functions of the proteins encoded by the genes. To reveal the function of each and every protein, investigation of protein localization at the subcellular level has become a central focus in this research area, since the localization and function of a protein is closely related. READ MORE

  4. 12. The spatiotemporal protein landscape of human cells

    Author : Lovisa Stenström; Emma Lundberg; Björn Högberg; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spatial proteomics; Immunofluorescence; Human Protein Atlas; Nucleolus; Cell cycle; Citizen science; Bioteknologi; Biotechnology;

    Abstract : This thesis focuses on the spatiotemporal mapping of proteins at a subcellular level. In other words, determining the cellular location of proteins over time. From a biological point of view, knowledge about protein location is fundamental to understand protein function. READ MORE

  5. 13. Selection of antigens for antibody-based proteomics

    Author : Lisa Berglund; Mathias Uhlén; Sören Brunak; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; epitope; antigen; antibody; affinity; protein; proteome; proteomics; bioinformatics; prediction; primer design; sequence similarity; Bioengineering; Bioteknik;

    Abstract : The human genome is predicted to contain ~20,500 protein-coding genes. The encoded proteins are the key players in the body, but the functions and localizations of most proteins are still unknown. READ MORE

  6. 14. Antibiotic resistance and pathogenesis of Streptococci with focus on Group A Streptococci

    Author : Feiruz Alamiri; Malmö Experimentell infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotika resistens; Bröstmjölk; Luftvägsinfektioner; Biofilm bildning; Internalisering; Persistens; HAMLET; Streptokocker; kolonisering; Streptococcus pneumoniae; biofilm formation; Internalisation; Persistence; Antibiotic resistance; Streptococcus pyogenes; Streptococcus agalactiae; HAMLET; Breast milk; Proteome; Virulence factors; Colonization;

    Abstract : Multi-drug resistant (MDR) infections remain the leading cause of death worldwide. MDR infections caused by Streptococcus pneumoniae (Spn), Streptococcus pyogenes (GAS) and Streptococcus agalactiae (GBS) are considered global threats to human health due to increased spread of antibiotic resistance and limited treatment options. READ MORE

  7. 15. OVULATION: Intra-ovarian mechanisms

    Author : Farnosh Sørensen Zakerkish; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovulation; Human;

    Abstract : Background: Ovulation is the central biological process involved in the menstrual cycle of women. Specifically, ovulation involves the tissue remodelling of the preovulatory follicle to achieve the rupture of the exterior follicle wall with the extrusion of the oocyte. READ MORE