Search for dissertations about: "Huntington’s disease."

Showing result 11 - 15 of 47 swedish dissertations containing the words Huntington’s disease..

  2. 11. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

    Author : Andy Mccourt; Biomarkörer vid hjärnsjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; weight loss; white adipose tissue; brown adipose tissue; peripheral symptoms; R6 2 mice; UCP1; CREB1; gene expression;

    Abstract : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. READ MORE

  4. 12. On neural transplantation in a rat model of Huntington’s disease : a graft survival study

    Author : Ulrika Mundt-Petersen; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell survival; huntington disease; rat model; Huntington disease;

    Abstract : .... READ MORE

  5. 13. β-cell dysfunction in Huntington's disease

    Author : Karl Bacos; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; secretion; Insulin; trafficking; R6 2 mouse; granule; exocytosis; neurodegeneration; huntingtin;

    Abstract : Huntington's disease (HD), a fatal neurodegenerative disorder, is associated with an increased risk of diabetes mellitus. The reason for this is unknown, but considering the functional similarities of neurons and the insulin secreting pancreatic β-cell, pathological mechanisms may be shared by both cell types and account for neuronal as well as endocrine dysfunction. READ MORE

  6. 14. Building the Bridge from Bench to Bedside: Ethical Issues in Translational Stem Cell Research

    Author : Kristina Hug; Medicinsk etik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Translational stem cell research; research ethics; values; experimental stem cell-based therapies; patient safety; treatment efficacy; treatment accessibility; first-in-human trials; Parkinson’s disease; Huntington’s disease; priority setting; right to withdraw; human biological material; informed consent;

    Abstract : Abstract in UndeterminedTranslational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. READ MORE

  7. 15. Towards a novel treatment of Huntington’s disease

    Author : Mouna Esmaeilzadeh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The function of the human brain is based on complex interactions between billions of neurons. The brain function declines as a result of normal aging, but is also disturbed in neuropsychiatric and neurodegenerative disorders. READ MORE