Search for dissertations about: "Hydroperoxides"

Showing result 1 - 5 of 22 swedish dissertations containing the word Hydroperoxides.

  2. 1. Mass Spectrometric Analysis of Oxylipins : Application to Cytochrome P450-Dependent Metabolism

    Author : Tomas Nilsson; Ernst Oliw; Johan Bylund; Mikael Hedeland; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epoxyalcohols; fatty acids; hydroperoxides; electrospray ionization; ichthyosis; CYP4; linear ion trap; fragmentation mechanism; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Biochemical Pharmacology; Biokemisk farmakologi;

    Abstract : Cytochrome P450 (CYP) family 4 constitutes monoxygenases responsible for hydroxylation of fatty acids and other lipids. For example, CYP4F3 metabolizes leukotrienes and CYP4F8 prostaglandin H. Importantly, six of the twelve CYP4 enzymes are orphans, i.e. READ MORE

  4. 2. Allergenic Oxidation Products from Fragrance Terpenes. Chemical Analysis and Determination of Sensitizing Potency

    Author : Johanna Rudbäck; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Autoxidation; Contact allergy; Essential oils; Fragrances; Hydroperoxides; Ionization techniques; Mass spectrometry; Prehapten; Sensitization; Skin; Structure-activity relationships; Terpenes;

    Abstract : The ubiquitous presence of fragrance compounds in consumer products has resulted in a high frequency of contact allergy to fragrances in the population. For prevention purposes and according to EU regulations, cosmetics must be labeled when containing the most prominent fragrance allergens in concentrations exceeding 0. READ MORE

  5. 3. Lipid peroxidation in vivo : Evaluation and application of methods for measurement

    Author : Eva Södergren; Uppsala universitet; []
    Keywords : Medical sciences; lipid peroxidation; hydroperoxides; F2-isoprostanes; MDA; prostaglandins; measurement; carbon tetrachloride; vitamin E; dietary fat quality; rapeseed oil; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

    Abstract : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. READ MORE

  6. 4. Analytical methodologies for common skin allergens : Organic thioureas, isothiocyanates and fragrance hydroperoxides in everyday life products

    Author : Ahmed Gamal Ramzi; Ulrika Nilsson; Anneli Julander; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemical analysis; contact allergy; chloroprene rubber; diethyl thiourea; ethyl isothiocyanate; fragrance hydroperoxides; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis describes analytical methodologies for the determination of important skin-sensitizing chemicals in two types of commercial items: chloroprene rubber and fragrance products which are both well-known to be associated with contact allergy.Chloroprene rubber (neoprene) is widely used in different applications and products, such as bags, gloves, wetsuits, braces, mouse pads et c. READ MORE

  7. 5. Limonene Hydroperoxides in Allergic Contact Dermatitis. Radical Formation, Sensitizing Capacity and Immunogenic Complex Formation

    Author : Staffan Johansson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; allergic contact dermatitis; contact allergy; immunogenic complex; limonene hydroperoxides; local lymph node assay; patch testing; radicals; sensitizing capacity; skin;

    Abstract : Contact allergy to fragrance compounds is an increasing problem in the western countries today. R-Limonene is one of the most common fragrance compounds; it is used in hygiene products and cosmetics as well as in industrial products such as hand cleansers and degreasers. READ MORE