Search for dissertations about: "Hydrophilic Interaction Liquid Chromatography"

Showing result 1 - 5 of 10 swedish dissertations containing the words Hydrophilic Interaction Liquid Chromatography.

2. 1. Hydrophilic Separation Materials for Liquid Chromatography

   Author : Petrus Hemström; Knut Irgum; Peter Schoenmakers; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatography; HILIC; Hydrophilic; Stationary phase; Chemistry; Kemi;

   Abstract : The main focus of this thesis is on hydrophilic interaction chromatography (HILIC) and the preparation of stationary phases for HILIC. The mechanism of HILIC is also discussed; a large part of the discussion has been adapted from a review written by me and professor Irgum for the Journal of Separation Science (ref 34). READ MORE

4. 2. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

   Author : Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Abstract : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. READ MORE

5. 3. Isocyanates, Amines and Alkanolamines : Sampling, Chromatography and Detection

   Author : Jakob B. Riddar; Marianne Dalene; Gunnar Skarping; Daniel Karlsson; Håkan Westberg; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Air-sampling; Isocyanates; Aromatic amines; Aliphatic amines; Alkanolamines; Hydrophilic Interaction Liquid Chromatography; Dry Denuder-Filter sampler; Liquid Chromatography–tandem Mass Spectrometry; Polyurethane Foam Extraction; Analytical Chemistry; analytisk kemi;

   Abstract : Isocyanates, aromatic-, aliphatic- and alkanolamines are commonly used in the industry today. Millions of workers in Europe are exposed. The most frequent health symptoms are respiratory and dermal disorder. Due to the health risk most of the compounds in this thesis are regulated by authorities and have occupational exposure limits (OELs). READ MORE

6. 4. Polyhydroxyl and Polyphosphorylcholine functionalized Silica for Hydrophilic interaction liquid Chromatography- Synthesis, characterization and application

   Author : Nhat Thi Hong Bui; Knut Irgum; Michael Lämmerhofer; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hydrophilic Interaction Chromatography; HILIC; silica; TRIS; acrylamide acrylate; ATRP; iniferter; “controlled living’’ radical polymerization; N; N′-methylenebisacrylamide; MPC; stationary phase; analytisk kemi; Analytical Chemistry;

   Abstract : This thesis focuses on the development of new stationary phases for use in hydrophilic interaction liquid chromatography using TRIS-based and phosphorylcholine typed monomers and porous silica particles as starting substrates. In this thesis, several ways of polymerizing highly hydrophilic mono­mers onto pore surfaces of silica supports are described, based on several “grafting from” schemes. READ MORE

7. 5. Study of retention mechanisms in Hydrophilic Interaction Chromatography by Nuclear Magnetic Resonance Spectroscopy

   Author : Adel Shamshir; Knut Irgum; Tobias Jonsson; Ngoc Phuoc Dinh; Torgny Fornstedt; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; HILIC; hydrophilic interaction chromatography; adsorption; STD-NMR; saturation transfer difference; retention mechanism; NMRD; solid state-NMR; Analytical Chemistry; analytisk kemi;

   Abstract : This thesis deals with investigations of the retention mechanisms in hydrophilic interaction liquid chromatography (HILIC) using nuclear magnetic resonance spectroscopy. The aims are to understand how the different types of stationary phases can influence the retention of various solutes and the adsorption abilities of solvent on stationary phases. READ MORE