Search for dissertations about: "Hydrophilic matrices"
Showing result 1 - 5 of 19 swedish dissertations containing the words Hydrophilic matrices.
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1. Mechanistic Modelling of Drug Dissolution and Matrix Formulations: Rotating Disc Dissolution, Dissolution in a Stagnant Medium, Swelling and Dissolving Matrix Systems
Abstract : Popular Abstract in Swedish Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. READ MORE
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2. Swelling of Cellulose Fibrillar Matrices and Gels
Abstract : One of the major challenges of today´s society is to find a sustainable way to create a living based on the resources on earth. It is a challenge that includes a transition from fossil-based materials to renewable/biodegradable raw materials and also the creation of an environmentally friendly circular material flow. READ MORE
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3. Development of LC-MS/MS Methods for the Analysis of Chiral and Achiral Pharmaceuticals and Metabolites in Aqueous Environmental Matrices
Abstract : This thesis describes the development of liquid chromatography tandem mass spectrometry (LC-MS/MS) methods for the trace analysis of active pharmaceutical ingredients (APIs) and their metabolites in aqueous environmental matrices. The research was focused on the development of chiral LC-MS/MS methods for the analysis of fluoxetine and metoprolol, as well as their chiral metabolites in environmental water samples. READ MORE
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4. Investigation of the functionality related characteristics of hydroxypropyl methylcellulose for the release from matrix tablets
Abstract : Hydrophilic matrix tablets are a compressed well mixed composite of drug substance and excipients including a hydrophilic polymer. When the tablet comes in contact with biological fluids, the hydrophilic polymer starts to dissolve, a process that decreases the water penetration through the tablet and involves dimensional changes of the tablet due to swelling of the solvated polymers. READ MORE
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5. Antioxidants in Andean food and meals
Abstract : Abstract The constant need to improve health and to prevent disease in Bolivia, especially in the Andean region with its extreme environmental conditions (high altitude and lower temperatures), motivated us to extend studies of antioxidant sources in foods and plants, since antioxidants are believed to have major health benefits. Spectrophotometric methods, such as ABTS (2, 2’- azinobis-3-ethylbenzotiazoline-6-sulfonic acid) and FRAP (ferric reduction antioxidant power), were used to evaluate antioxidant activity. READ MORE