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Showing result 6 - 10 of 10 swedish dissertations matching the above criteria.

  2. 6. Neural circuits engaged in mastication and orofacial nociception

    Author : Tuija Athanassiadis; K-G Westberg; Sten Grillner; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rhythmical jaw movements; central pattern generator; trigeminal system; rabbit; Rat; c-Fos; nociceptors; muscle pain; muscle spindle afferents; glutamate; Neurophysiology; Neurofysiologi; fysiologi; Physiology;

    Abstract : A deeper understanding of both movement control and the effects of nociceptor inputs on our motor systems is critical for proper clinical diagnosis of musculo-skeletal dysfunctions and for development of novel rehabilitation schemes. In the jaw system, masticatory movements are produced by a central pattern generator (CPG) located in the brainstem. READ MORE

  4. 7. Paracrine control of glucagon secretion in the pancreatic α-cell: Studies involving optogenetic cell activation

    Author : Caroline Miranda; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Glucagon; α-Cell; Optogenetics;

    Abstract : ABSTRACT The mechanisms controlling glucagon secretion by α-cells in islets of Langerhans were studied. We generated mice with the light-activated ion channel ChR2 specifically expressed in β-, α-, and δ-cells, and explored the spatio-temporal relationship between cell activation and glucagon release. READ MORE

  5. 8. Signal Transduction of Glucagon Secretion

    Author : Elaine Vieira; Erik Gylfe; Lena Eliasson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; secretion; glucagon; store-operated channels; calcium; diabetes; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Diabetes mellitus is a bihormonal disorder with hyperglycemia due to deficiency of insulin and hypersecretion of glucagon. To improve diabetes treatment it is important to clarify the signal transduction of glucagon secretion. READ MORE

  6. 9. The Cross-Talk between GABA Signalling and Metabolic Hormones in the Brain and Pancreatic Islets

    Author : Yang Jin; Bryndis Birnir; Vidar Gundersen; Uppsala universitet; []
    Keywords : ;

    Abstract : GABA is a well-known neurotransmitter that can be synthesized in the central nervous system (CNS) and, interestingly, also in pancreatic islets. Once released, GABA activates GABA-A channels tonically or transiently resulting in different physiological functions. READ MORE

  7. 10. Growth of parathyroid glands : genetic and functional aspects

    Author : Stiina Välimäki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Parathyroid; primary hyperparathyroidism; secondary hyperparathyroidism; parathyroid carcinoma; chromosome 1; HDAC1; HRPT2; CASR; CAS; VDR; PTH; loss of heterozygosity; tumor suppressor gene; patch clamp; membrane potential; K channels;

    Abstract : Ca2+ is an essential ion with a variety of important functions in the body and it is crucial that the Ca2+ levels are precisely regulated. One of the hormones regulating these processes is parathyroid hormone (PTH) secreted from the parathyroid glands. READ MORE