Search for dissertations about: "I. Das"

Showing result 1 - 5 of 70 swedish dissertations containing the words I. Das.

  2. 1. Quantifying effects of antimicrobial drug combinations by modelling and simulation

    Author : Chenyan Zhao; Lena Friberg; Elisabet I. Nielsen; Shampa Das; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics and pharmacodynamics; modelling and simulation; antibiotic combination; model-based translation; antibiotic resistance; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Antibiotic resistance is becoming an accelerating issue, both in the treatment of nosocomial infections and for public health in general. There is a pressing need for innovative methods to understand how available antibiotics could be combined to overcome and limit the emergence of resistance. READ MORE

  4. 2. Hydrolytic and oxidative catalytic activities of bio-inspired dinuclear metal complexes

    Author : Biswanath Das; Kemisk fysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinorganic Chemistry; Metalloenzymes; Catalyst; Transition states; Phosphoesterase;

    Abstract : A number of homo- and heterodinuclear complexes have been synthesized as structural and functional models for the the active sites of phosphoesterases and soluble methane monooxygenases. The complexes are based on four new dinucleating ligands containing a central, potentially bridging, phenolate moiety. READ MORE

  5. 3. Hitting the right targets : a study of molecular mediators of sensitivity to novel potential targeted therapies in cutaneous malignant melanoma

    Author : Ishani Das; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cutaneous malignant melanoma (CMM) is the deadliest form of skin cancer with a 5-year overall survival (OS) rate of less than 10% among patients diagnosed with disseminated disease. During the past decade the emergence and use of novel targeted therapy and immunotherapy has significantly increased the 5-year OS rate (34%). READ MORE

  6. 4. A theoretical perspective on photoinduced reactions - based on quantum chemical models and non-adiabatic molecular dynamics

    Author : Sambit Das; Michael Odelius; Mårten Ahlquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Non-adiabatic dynamics; Molecular dynamics; Surface hopping; TDDFT; X-ray absorption spectroscopy; kemisk fysik; Chemical Physics;

    Abstract : The broad range of applications for photochemical reactions is the result of light-matter interaction at the electronic level. The diverse application of photochemistry in various fields, including photovoltaic materials, molecular switches, and biological systems are due to electronic and structural transformations induced by photoexcitation as well as molecular alteration due to electron and charge transfer. READ MORE

  7. 5. Understanding the role of non-coding RNAs in skin homeostasis and cancer

    Author : Kunal Das Mahapatra; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The epidermis is a stratified epithelium with continuous self-renewing capacity. As the outermost layer of our body, it provides a protective barrier against external trauma, produces pigmentation, and keeps the skin hydrated. Keratinocytes are the primary constituent cells type within the epidermis. READ MORE