Search for dissertations about: "I. Ralph Edwards"

Found 3 swedish dissertations containing the words I. Ralph Edwards.

  2. 1. Quantitative methods to support drug benefit-risk assessment

    Author : Ola Caster; Love Ekenberg; Mats Danielson; I. Ralph Edwards; Sir Michael Rawlins; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; data- och systemvetenskap; Computer and Systems Sciences;

    Abstract : Joint evaluation of drugs’ beneficial and adverse effects is required in many situations, in particular to inform decisions on initial or sustained marketing of drugs, or to guide the treatment of individual patients. This synthesis, known as benefit-risk assessment, is without doubt important: timely decisions supported by transparent and sound assessments can reduce mortality and morbidity in potentially large groups of patients. READ MORE

  4. 2. Statistical methods for knowledge discovery in adverse drug reaction surveillance

    Author : G. Niklas Norén; Rolf Sundberg; I. Ralph Edwards; Heikki Mannila; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mathematical statistics; Matematisk statistik; Mathematical Statistics; matematisk statistik;

    Abstract : Collections of individual case safety reports are the main resource for early discovery of unknown adverse reactions to drugs once they have been introduced to the general public. The data sets involved are complex and based on voluntary submission of reports, but contain pieces of very important information. READ MORE

  5. 3. Safety of Medication in Paediatrics

    Author : Kristina Star; Karin Nordin; I Ralph Edwards; Richard Irvin Cook; Uppsala universitet; []
    Keywords : paediatrics; adverse drug reaction; drug-related problem; medication error; patient safety; individual case safety reports; pharmacovigilance; medication; nurses; health care personnel; dosage form; NSAID; dosing; prescription; antipsychotic medicines; postmarketing surveillance; Medicinsk vetenskap; Medical Science;

    Abstract : Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge.Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. READ MORE