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Showing result 11 - 15 of 15 swedish dissertations matching the above criteria.

  2. 11. The Stress Hypothesis : Implications for the induction of diabetes-related autoimmunity in children?

    Author : Anneli Sepa; Ann Frodi; Johnny Ludvigsson; Gunilla Bohlin; Linköpings universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Psychological stress; parenting stress; attachment security; serious life events; children; attitudes; Type I diabetes; beta-cell autoantibodies; prediction; etiology; Medicine; Medicin;

    Abstract : Background: Second to Finland, Sweden has the world’s highest incidence of type 1 diabetes. Experiences of serious life events have retrospectively been shown to constitute a risk factor for the development of this disease, probably via the biological stress response. READ MORE

  4. 12. Immunity against porcine islet xenografts in man

    Author : Ellinor Lindeborg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pig islets xenotransplantation; Type 1 diabetes; xenoimmune antibodies; IgG1; T cells.;

    Abstract : Due to the lack of organs for clinical transplantation, alternative sources have been investigated. One solution to this shortage could be xenotransplantation, i.e. the transplantation of organs/cells across species barriers. READ MORE

  5. 13. Aspects of autoantibody epitopes in type 1 diabetes

    Author : Hanna Skärstrand; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Minor autoantigens Neuropeptide Y.; Affinity; ZnT8 autoantibodies; Autoimmune type 1 diabetes;

    Abstract : Type 1 diabetes (T1D) is strongly associated with autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), insulinoma-associated protein 2 (IA-2A) and the most recently identified zinc T8 transporter (ZnT8A). Together or alone, they are important both to predict T1D and to classify diabetes at the time of clinical onset. READ MORE

  6. 14. Autoantibodies as markers of beta-cell autoimmunity in children

    Author : Hanna Holmberg; Johnny Ludvigsson; Mona Landin-Olsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Autoantibodies; Beta-cell autoimmunity; Children; Breast-feeding; HLA haplotypes; Insulin gene; Paediatric medicine; Pediatrisk medicin;

    Abstract : Type 1 diabetes (T1D) is a chronic disease caused by destruction of the insulin producing beta-cells in the pancreas. The incidence of T1D has increased rapidly, especially in the Western world and among young children. READ MORE

  7. 15. Triggers of autoimmunity. Studies on gestational events

    Author : Sabina Lindehammer; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet autoantibodies; pregnancy; type 1 diabetes; celiac disease;

    Abstract : Objective The primary aim of this thesis was to test whether gestational exposure to environmental factors may induce islet autoimmunity. The second aim was to determine to what extent the exposure to viruses or other environmental factors is a risk factor for type 1 diabetes in the offspring. READ MORE