Search for dissertations about: "IAP-inbibitors"

Found 1 swedish dissertation containing the word IAP-inbibitors.

2. 1. Tumour Survival Signals and Epigenetic Gene Silencing in Multiple Myeloma : Implications for Biology and Therapy

   Author : Charlotte Fristedt Duvefelt; Helena Jernberg-Wiklund; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple myeloma; Polycomb; apoptosis; cIAP2; IAP-inbibitors; proteasome inhibitors; LBH589; PPP; DZNep;

   Abstract : This thesis is focused on multiple myeloma (MM), a haematological malignancy that still remains incurable. The pathogenesis of MM is not fully understood and there is a large intra-tumour and interclonal genetic variation in MM patients. READ MORE