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Showing result 1 - 5 of 7 swedish dissertations matching the above criteria.

  2. 1. Interstrand Crosslinks - Induction and repair

    Author : Daniel Vare; Dag Jenssen; Klaus Erixon; Fredrik Johansson; Marcel Tijsterman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ICL; DNA repair; interstrand crosslink; psoralen; molekylärgenetik; Molecular Genetics;

    Abstract : DNA crosslinking agents exhibit a variety of DNA lesions, such as monoadducts, DNA-DNA interstrand or intrastrand crosslinks or DNA-protein crosslinks. Agents that produce interstrand crosslinks (ICLs) exist naturally and are widely used in chemotherapy. Therefore, it is important to understand how the lesions induced by these agents are repaired. READ MORE

  4. 2. Heterogeneous Degradation and Recyclability of PP Studied by Imaging Chemiluminescence

    Author : Mikael Hamskog; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Teknik; Technological sciences; recyclability; mapping; surface; heterogeneity; heterogeneous; evaporation; ageing; hamamatsu; russel; ICL; CL; Irganox 1010; Irganox 1076; oxidation; hydroperoxide; radical; carbonyl; luminescence; chemiluminescence; imaging chemiluminescence; recycling; stabilization; polypropylene; degradation;

    Abstract : Oxidative degradation is a serious threat to long-term use and recyclability of polymers. Successful recycling of polymeric quality products requires characterization of the polymer material after reprocessing and use. READ MORE

  5. 3. Finding synergies for cancer treatment : new ways to modulate DNA damage repair by CX3CR1 and PFKFB3 inhibition

    Author : Jemina Lehto; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The goal of targeted cancer therapy is to selectively kill cancer cells based on their molecular survival mechanisms. DNA repair is as a promising cancer target as many cancers have chronic replication stress and deficiencies in the DNA damage response. READ MORE

  6. 4. New Approaches to Investigate and Prevent Oxidation of Polypropylene

    Author : Petter Eriksson; KTH; []
    Keywords : oxidation; polypropylene; oxidative spreading; antioxidants; hyperbranched antioxidants;

    Abstract : When employing chemiluminescence to evaluate stabiliserperformance in a polymer, the induction time or the time toreach maximum chemiluminescence intensity is often used. Insuch an experiment the longest part of the experiment isnormally the time before the oxidation starts. READ MORE

  7. 5. Imaging chemiluminescence applied to oxidation of rubber materials and polyamide

    Author : Gustav Ahlblad; KTH; []
    Keywords : ;

    Abstract : In this thesis the heterogeneous nature of thermal oxidationof polymer materials have been investigated by imagingchemiluminescence (KL). The issues of oxidation depth profilesand physical spreading of oxidation in rubbers materials andpolyamide have been addressed. READ MORE