Search for dissertations about: "IFN-[alpha]"
Showing result 1 - 5 of 25 swedish dissertations containing the word IFN-[alpha].
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1. Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells
Abstract : The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendritic cells (pDCs). READ MORE
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2. Interferons in immunity to chlamydia pneumoniae
Abstract : The cytokine IFN-gamma is the architect behind an amazing immunological program of host resistance to intracellular bacterial and protozoan infections. IFN-gamma activates macrophages, making them into inhospitable habitats for parasites attempting to grow inside them. READ MORE
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3. Humoral and cellular immune responses to proteins encoded by the hepatitis C virus
Abstract : The hepatitis C virus (HCV) was the first described human pathogen of the hepaciviruses, a new genus within the flaviviridae family. A characteristic feature of HCV is that it has a high genetic heterogenecity. It is believed that the immune response is of vital importance to prevent, control, and to eradicate HCV infections. READ MORE
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4. Studies of the recognition and activation of natural killer cells
Abstract : Natural killer (NK) cells mediate part of the innate immune response that impedes the spread of invading microorganisms and shapes the downstream adaptive immune response. NK cells spontaneously kill tumor cells and other cells upon contact. Killing requires engagement of germline encoded receptors that mediate positive and negative signals. READ MORE
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5. Monoclonal antibodies and cytokines for therapy of patients with advanced colorectal carcinoma : a clinical and immunological study
Abstract : There is a great need for developing and improving treatment alternatives in colorectal carcinoma (CRC). The tumour associated antigen (TAA) GA733/CO17-1A is expressed by more than 90% of all CRCs, on the majority of both primary and metastatic CRC cells. READ MORE