Search for dissertations about: "IFN-γ"

Showing result 1 - 5 of 174 swedish dissertations containing the word IFN-γ.

  1. 1. Function of natural killer cells in Helicobacter pylori infection and gastric cancer

    Author : Åsa Lindgren; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Natural killer cells; Helicobacter pylori; gastric cancer; IFN-γ; TLR;

    Abstract : Helicobacter pylori infection is one of the most wide-spread infections in the world and causes a chronic inflammation in the gastrointestinal mucosa characterised by increased production of IFN-γ and is associated with an increased risk of developing gastric cancer. The mechanisms behind the development of gastric cancer in H. READ MORE

  2. 2. Immune maturation in early childhood and the influence of herpesvirus infections

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Ebba Sohlberg; Stockholms universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immune differentiation; monocytes; NK cells; B cells; T cells; Epstein-Barr virus; EBV; cytomegalovirus; CMV; IFN-γ; immunologi; Immunology;

    Abstract : The quality of immune responses develops from birth into adulthood and in the context of the host microbial environment. The aim of this work was to study immune maturation during childhood, and how this process can be affected by the common herpesviruses; Epstein-Barr virus (EBV) and cytomegalovirus (CMV). READ MORE

  3. 3. Immunotherapy and COX-2 inhibition against malignant brain tumors

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Sofia Eberstål; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant brain tumors; immunotherapy; IFN-γ; GM-CSF; COX-2 inhibition;

    Abstract : Glioblastoma multiforme (GBM) is the most common primary brain tumor in the central nervous system and the prognosis is very poor despite conventional therapies including surgery, chemo- and radiotherapy. Peripheral vaccination with irradiated tumor cells represent a novel therapy that targets both dividing and non-dividing tumor cells and minimizes the risk of therapy resistance by presenting multiple tumor antigens. READ MORE

  4. 4. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Annika K. Andersson; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; β-cell; Cyclooxygenase; Cytokine; Diabetes; IFN-γ; IL-1β; iNOS; Insulin; Melatonin; Nitric oxide; Pancreatic islets; Phospholipase D; Prostaglandin E2; Streptozotocin; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi;

    Abstract : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. READ MORE

  5. 5. Mechanisms of the intracellular survival of Francisella tularensis

    University dissertation from Umeå : Umeå universitet

    Author : Linda Tancred; Umeå universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; Igl; MglA; J774; IFN-γ; RNS; ROS; phagosome; MEDICINE Microbiology; immunology; infectious diseases Microbiology Clinical bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Klinisk bakteriologi; mikrobiologi; Microbiology;

    Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE