Search for dissertations about: "IFN-beta"

Showing result 1 - 5 of 17 swedish dissertations containing the word IFN-beta.

  2. 1. Tolerance Mechanisms in Collagen-Induced Arthritis an Animal Model of Rheumatoid Arthritis

    Author : Alexandra Treschow; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; Tolerance; Regulation; IFN-beta; Macrophages; Immunology; serology; transplantation; Immunologi; serologi; Arthritis; Collage; rheumatology locomotion; muscle system; Skelett; muskelsystem; reumatologi;

    Abstract : Collagen-induced arthritis (CIA) is one of the most commonly used animal models for Rheumatoid arthritis (RA). CIA is induced in susceptible mouse strains after immunization with heterologous type II collagen (CII). In mice of the H-2q haplotype rat CII (rCII) is used whereas in mice of the H-2r haplotype bovine CII is utilized. READ MORE

  4. 2. Immunological effects of interferon-beta and glatiramer acetate in multiple sclerosis

    Author : Yassir Hussien; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Multiple sclerosis; Interferon-beta; Glatiramer acetate; Dendritic cells; Mononucealar cells;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which results in demyelination, axonal loss and neurological deficits. The aetiology is unknown, however, immunopathological events, which are believed to be of an autoimmune nature, are considered to be responsible for the development of the disease. READ MORE

  5. 3. Interferon-beta treatment in multiple sclerosis : analysis of neutralizing antibodies

    Author : Ajith Sominanda; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a disabling chronic neurological disease with a significant impact on patients lives. There is no cure for MS, but recombinant interferon beta (IFN-beta) is currently the most established disease modifying therapy. READ MORE

  6. 4. Regulation of CNS inflammation upon T cell interaction with CNS resident cells

    Author : Ingrid Teige; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurofysiologi; neuropsykologi; Neurologi; neurophysiology; neuron; glia; CNS; T cell; cytokine; immunoregulation; MS; EAE;

    Abstract : Multiple Sclerosis (MS), is a neurologic, autoimmune disease characterized by CNS immune cell infiltration and demyelination. To experimentally study MS, we have utilized the mouse model Experimental Autoimmune Encephalomyelitis (EAE). EAE is induced through immunization with myelin antigens, which elicits an autoreactive Th1 cell response. READ MORE

  7. 5. Studies on dendritic cells in multiple sclerosis and experimental allergic encephalomyelitis

    Author : Yu-Min Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) resulting in demyelination, axonal loss and, ultimately, formation of gliotic scar tissue in the brain and spinal cord. MS remains the major disabling neurological illness of young adults of North European origin. READ MORE