Search for dissertations about: "IFN-gamma"

Showing result 16 - 20 of 155 swedish dissertations containing the word IFN-gamma.

  2. 16. Immunological studies of adenoids in children : relation to atopy

    Author : Georgios Papatziamos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adenoids; atopy; flow cytometry; immunohistochemistry; IgE; IL-2; IL-4; IFN-gamma; epsilonGL transcripts; IgE cells; IgE plasma cells;

    Abstract : The nasopharyngeal tonsil or adenoids is in constant interaction with our environment with every breath we take. This organ, rich in B cells, contains all the immunocompetent cells necessary for an interaction with T cells, exerted through secretion of cytokines and resulting in the production of immunoglobulins and the formation of memory cells. READ MORE

  4. 17. Immune mechanisms in atherosclerosis

    Author : Ejaz Ahmed; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; diabetes; stroke; rheumatoid arthritis; autoantibodies; anticardiolipin; oxidized LDL; hypercholesterolernia; IFN-gamma TNF-alpha IL-1beta IL-1Ra.;

    Abstract : Atherosclerosis is a multifactorial chronic inflammatory disorder. Humoral immune factors as anticardiolipin antibodies (aCL), anti-oxLDL antibodies, circulating immune complexes (CICs), and proinflammatory cytokines such as IFN-gamma, TNF-alpha and EL-1beta have been implicated in atherogenesis. READ MORE

  5. 18. Experimental Chagas disease

    Author : John Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Trypanosoma cruzi; NK cells; cytotoxicity; IFN-gamma; IL-12; IFN-alpha beta; Chagas disease; polymyositis; myocarditis; genotype dependence and Toll-like receptors.;

    Abstract : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. READ MORE

  6. 19. Enhancing T cell mediated immunity in DNA vaccination

    Author : Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

    Abstract : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. READ MORE

  7. 20. Platelet-activating factor and lysophospatidylcholine in oxidized low density lipoprotein-mediated immune activation

    Author : Yihui Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; oxidized LDL; platelet-activating factor PAF ; Iysophosphatidylcholine LPC ; anti-MHC class II antibodies; antibody; T cells; cytokine; IFN-[gamma]; IL-6; IL-4; TNF-[alpha]; a PAF specific receptor antagonist-WEB2170;

    Abstract : Inflammation is a risk factor for development of cardiovascular disease, as in addition to known risk factors such as hypertension, hyperlipidemia, smoking and diabetes. Patients with inflammatory diseases including SLE have an enhanced risk of cardiovascular disease. READ MORE