Search for dissertations about: "IFN"

Showing result 11 - 15 of 578 swedish dissertations containing the word IFN.

  2. 11. Immune maturation in early childhood and the influence of herpesvirus infections

    Author : Ebba Sohlberg; Eva Sverremark-Ekström; Eleanor Riley; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immune differentiation; monocytes; NK cells; B cells; T cells; Epstein-Barr virus; EBV; cytomegalovirus; CMV; IFN-γ; immunologi; Immunology;

    Abstract : The quality of immune responses develops from birth into adulthood and in the context of the host microbial environment. The aim of this work was to study immune maturation during childhood, and how this process can be affected by the common herpesviruses; Epstein-Barr virus (EBV) and cytomegalovirus (CMV). READ MORE

  4. 12. Antibacterial peptides - key players in host defense at epithelial surfaces

    Author : Mette Eliasson; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosa; epithelium; pharyngitis; Innate immunity; Streptococcus pyogenes; antibacterial peptides; IFN-gamma; CXCL9 MIG; chemokines;

    Abstract : Innate host defense mechanisms at epithelial surfaces are important to prevent bacterial invasion. Streptococcus pyogenes, group A streptococcus (GAS), has an affinity for epithelial cells and cause pharyngitis. During streptococcal pharyngitis, high concentrations of the chemokines CXCL9/MIG, CXCL10/IP-10, CXCL11/I-TAC were found in tonsil fluid. READ MORE

  5. 13. Innate and adaptive immunity in genital HSV-2 infection: Implications for vaccine development

    Author : Ali M Harandi; Göteborgs universitet; []
    Keywords : genital herpes infection; natural antibody; CD4 T cells; CD8 T cells; IFN-g; IL-12; IL-18; CC chemokines; dendritic cells.;

    Abstract : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa and is the most common case of genital ulcers in humans. Despite numerous studies, little is known about the mechanisms involved in immune protection and no anti-herpes vaccine has been developed to date. READ MORE

  6. 14. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

    Author : Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. READ MORE

  7. 15. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines

    Author : Annika K. Andersson; Stellan Sandler; Nils Welsh; Décio L. Eizirik; Nils Billestrup; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; β-cell; Cyclooxygenase; Cytokine; Diabetes; IFN-γ; IL-1β; iNOS; Insulin; Melatonin; Nitric oxide; Pancreatic islets; Phospholipase D; Prostaglandin E2; Streptozotocin; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. READ MORE