Search for dissertations about: "IGF binding proteins IGFBP"
Showing result 1 - 5 of 28 swedish dissertations containing the words IGF binding proteins IGFBP.
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1. Insulin and IGF-I in type 1 diabetes
Abstract : Patients with type I diabetes have alterations in the GH/IGF system with reduced levels of circulating IGF-I, as well as other disturbances in the components of the IGF system.Alterations of both local and circulating IGF-I and its binding proteins (IGFBPs) have been associated with metabolic and vascular manifestations of diabetes and also with atherosclerosis. READ MORE
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2. The IGF-IGFBP system in aerobic exercise : with focus on skeletal muscle
Abstract : Activity induced skeletal muscle adaptation has been suggested to be mediated largely by intrinsic factors, such as insulin-like growth factor (IGF)-I. IGF-I stimulates muscle glucose and amino acid uptake and promotes anabolism. READ MORE
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3. Novel insulin-like growth factor-binding protein proteases : detection and characterization
Abstract : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. READ MORE
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4. Smooth muscle hypertrophy and the IGF-system
Abstract : Insulin-like growth factor-! (IGF-I) has both metabolic and mitogenic effects on smooth muscle cells (SMCs). The effects of IGF-I are modified by a group of binding proteins (IGFBPs). The present study was devoted to smooth muscle hypertrophy and the IGF-system in smooth muscle under different conditions. READ MORE
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5. Regulation and actions of insulin-like growth factor binding proteins in vascular smooth muscle cells
Abstract : Insulin-like growth factor-I (IGF-I) has multiple actions on vascular smooth muscle cell (VSMCs) function. In the circulation and in extracellular fluids, IGF-I is complexed to high affinity IGF-binding proteins (IGFBPs), which modulate IGF-I bioactivity. The present study focused on expression and regulation of IGFBPs in VSMCs. READ MORE