Search for dissertations about: "IGF-1"

Showing result 11 - 15 of 102 swedish dissertations containing the word IGF-1.

  1. 11. The GH-IGF-1 Axis in Postmenopausal Women with Abdominal Obesity

    Author : Celina Franco Ramos; Göteborgs universitet; []
    Keywords : ;

    Abstract : Abdominal obesity is associated with blunted growth hormone (GH) secretion. GH treatment in abdominally obese men reduces visceral adipose tissue (VAT) and improves the metabolic profile. READ MORE

  2. 12. GH, IGF-1 and insulin in the regulation of lipid and lipoprotein metabolism

    Author : Fredrik Frick; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth-hormone; insulin-like growth factor-I; insulin; lipoprotein lipase; adipose tissue; muscle tissue; VLDL secretion;

    Abstract : It is well known that growth hormone (GH) has profound effects on lipid and lipoprotein metabolism. Insulin-like growth factor-I (IGF-I) is believed to mediate some of the effects of GH via endocrine and paracrine mechanisms. Moreover, both GH and IGF-I are known to influence insulin secretion. READ MORE

  3. 13. The GH/IGF-1 system during surgery and catabolism : focus on metabolism and heart function

    Author : Mats Wallin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : GH plays a role in both anabolism and catabolism. The anabolic properties of GH are mediated by circulating (endocrine) and locally secreted (paracrine) IGF-1. It is thus the IGF-1 response after increased GH secretion that determines whether metabolism will be anabolic or catabolic. READ MORE

  4. 14. Alcohol and the effect on some appetite-regulating hormones in man

    Author : Jan Calissendorff; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Leptin; ghrelin; octanoylated; PYY3-36; GLP-1; obestatin; alcohol; NPY; IGF-1; IGFBP-1; insulin; glucose; testosterone; cortisol; catecholamines;

    Abstract : Beverage containing alcohol has been used for centuries to stimulate appetite. Ingestion of a moderate amount of alcohol increase energy intake. Regulation of food intake is complex. Several factors cooperate such as neural impulses from sensory organs; sight, smell, gut distension, social setting, memory, current energy status and hormones. READ MORE

  5. 15. Studies on N-linked glycosylation in proliferation and viability of normal and tumor cells in vitro

    Author : Magdalena Carlberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Apoptosis; DNA synthesis; IGF-1 receptor; HMG-CoA reductase; lovastatin; mevalonate; N-linked glycosylation; PDGF; SV40-transformation; tumor; tunicamycin.;

    Abstract : A number of studies suggest a critical role of N-linked glycosylation for cellular proliferation. In addition, many transformed and tumor cells have an altered 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity and an increased N-linked glycosylation. READ MORE