Search for dissertations about: "IGF2-H19"

Showing result 1 - 5 of 6 swedish dissertations containing the word IGF2-H19.

  2. 1. Transcriptional Silencing in the Imprinted Igf2-H19 Loci: The Mystique of Epigenetics

    Author : Vasudeva Ginjala; Andreas Paldi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Imprinting; DNA methylation; IGF2-H19; CTCF; ZFPs; PARP; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Genetics; genetik;

    Abstract : Genomic imprinting marks a subset of autosomal loci expressed in parent of origin-dependent monoallelic expression in a non-Mendelian fashion. To restore totipotency and to reset the imprint according to the sex of the individual, the mark must be erased during germline development. READ MORE

  4. 2. The Epigenetics of Gene Transcription and Higher Order Chromatin Conformation

    Author : Vijay Kumar Tiwari; Rolf Ohlsson; Terumi Kohwi-Shigematsu; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; DNA-protein interactions; Nuclear organization; Transcriptional regulation; Higher order chromatin conformations; Epigenetic reprogramming; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

    Abstract : It is becoming increasingly clear that long-range control of gene expression is mediated through direct physical interactions between genes and regulatory elements, either intra- or interchromosomally. In addition to transcriptional initiation, formation of active chromatin hubs seem to be crucial for increased transcriptional efficiency as well as insulation from neighbouring heterochromatic environment. READ MORE

  5. 3. Differential microRNA and metabolic expressions in neuroendocrine and cervical carcinomas

    Author : Patrick Scicluna; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : MicroRNAs (miRNAs) are important regulators of many biological processes involved in cancer development and progression. However, the functional roles of miRNAs in some cancer types are still poorly understood. READ MORE

  6. 4. Epigenetic Regulation of Genomic Imprinting and Higher Order Chromatin Conformation

    Author : Gholamreza Tavoosidana; Rolf Ohlsson; Job Dekker; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Epigenetic; Imprinting; Chromatin; CTCF; H19 ICR; 4C; Utvecklingsbiologi; Biology; Biologi;

    Abstract : The genetic information encoded by the DNA sequence, can be expressed in different ways. Genomic imprinting is an epigenetic phenomenon that results in monoallelic expression of imprinted genes in a parent of origin-dependent manner. Imprinted genes are frequently found in clusters and can share common regulatory elements. READ MORE

  7. 5. Epigenetic Regulation of Higher Order Chromatin Conformations and Gene Transcription

    Author : Anita Göndör; Reinald Fundele; Thomas Graf; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Genomic imprinting; Chromatin; Epigenetics; Cancer; Developmental biology; Utvecklingsbiologi;

    Abstract : Epigenetic states constitute heritable features of the chromatin to regulate when, where and how genes are expressed in the developing conceptus. A special case of epigenetic regulation, genomic imprinting, is defined as parent of origin-dependent monoallelic expression. READ MORE