Search for dissertations about: "IGFBP protease"

Showing result 1 - 5 of 6 swedish dissertations containing the words IGFBP protease.

  2. 1. The IGF-IGFBP system in aerobic exercise : with focus on skeletal muscle

    Author : Ulrika Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : IGF-I; IGFBP-1; microdialysis; exercise; IL-6; calpain;

    Abstract : Activity induced skeletal muscle adaptation has been suggested to be mediated largely by intrinsic factors, such as insulin-like growth factor (IGF)-I. IGF-I stimulates muscle glucose and amino acid uptake and promotes anabolism. READ MORE

  4. 2. Novel insulin-like growth factor-binding protein proteases : detection and characterization

    Author : Jing Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : IGFs; IGFBP-1. IGFBP-3; azurocidin HBP CAP37; IGFBP protease; gender;

    Abstract : Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins (IGFBP-1 to -6) control the availability of IGFs (IGF-I and IGF-II) to their receptors. READ MORE

  5. 3. Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control

    Author : Ingmar Zachrisson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Type 1 diabetes; Puberty; Adolescence; Metabolic Control; IGF-I; IGFBP-1; IGFBP-3; Proteases; Leptin;

    Abstract : It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved therapeutic approaches. READ MORE

  6. 4. Proteolysis of insulin-like growth factor-binding protein-1, -2 and -4 : function of fragments

    Author : Katrin Brandt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Insulin-like growth factor;

    Abstract : The insulin-like growth factors (IGF-I and IGF-II) stimulate cell growth, survival and differentiation, and have insulin-like activity. A family of six IGF-binding proteins (IGFBP-1 through -6) bind to IGFs with high affinity and modulate their activity in the circulation and locally at cell-surface receptors. READ MORE

  7. 5. The insulin-like growth factor system : effects of circulating proteases

    Author : Sara Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The insulin-like growth factor-I and -II (IGF-I/-II) are peptide hormones important for growth and metabolism. They stimulate cell proliferation and differentiation and inhibit apoptosis. In addition, they have insulin-like effects on glucose and amino acid metabolism. READ MORE