Search for dissertations about: "IL- 10"

Showing result 1 - 5 of 476 swedish dissertations containing the words IL- 10.

  1. 1. Regulation of growth, differentiation and survival of B-chronic lymphocytic leukemia cells

    Author : Ola Söderberg; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; B-CLL; B cells; IL-2; IL-4; IL-10; IL-15; CD40-stimulation; SAC; Thioredoxin; proliferation; differentiation; survival; in vitro; EBV; Patologi; Pathology; Patologi; Pathology; patologi;

    Abstract : Chronic lymphocytic leukemia of B cell type (B-CLL) is the most commonform of leukemia in the Western countries. The signals regulating theexpansion of the B-CLL clone in vivo is yet far from being fully understood. READ MORE

  2. 2. Immunological mechanisms involved in seasonal pollen allergy and allergen-specific immunotherapy

    Author : Robert Movérare; Uppsala universitet; []
    Keywords : Medical sciences; Allergy; birch pollen; IFN-g; IgE; IgG; IgG4; IL-4; IL-5; IL-10; IL-13; immunotherapy; PBMC; rush immunotherapy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; lungmedicin; Lung Medicine;

    Abstract : Th1/Th2-like T-cell responses were studied by stimulating peripheral blood mononuclear cells (PBMCs) with allergens or antigens followed by restimulation with mitogens to induce high cytokine synthesis. Allergen-stimulation in vitro induced Th2-skewed cytokine synthesis by PBMCs from birch-pollen-allergic patients. READ MORE

  3. 3. Corrosion resistant alumina-forming alloys for lead-cooled reactors

    Author : Jesper Ejenstam; Inger Odnevall Wallinder; Il Soon Hwang; KTH; []

    Abstract : Generation IV nuclear power technologies provide attractive solutions to the common issues related to conventional nuclear power plants currently in operation worldwide. Through a significant reduction of the long-term radiotoxicity of nuclear waste, a more efficient use of nuclear fuel resources, and implementation of inherent safety features, Generation IV will make nuclear power sustainable and thus increase the public acceptance of nuclear power. READ MORE

  4. 4. Modulation of cellular innate immune responses by lactobacilli

    Author : Mattias Karlsson; Jana Jass; Robert Brummer; Gilbert Donders; Örebro universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; cytokines; immunomodulation; lactobacilli; probiotics; urinary tract infections; urothelium; Biology; Biologi;

    Abstract : Lactobacillus is a genus of lactic acid bacteria frequently used as healthpromoting probiotics. Using probiotics to treat or prevent infections is a novel experimental approach with vast impact on future therapy. READ MORE

  5. 5. Functional analysis of the -1087 single nucleotide polymorphism in the IL-10 promoter region

    Author : Lena Larsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-10; B cells; Sp1; transcription factors; gene expression;

    Abstract : Interleukin (IL) 10 is recognized as a pro-inflammatory cytokine that promotes B cell proliferation. The objectives of the present series of studies were to analyze (i) differences in transcription factor binding to the -1087 IL-10 gene polymorphism in B cells, (ii) the influence of the A to G nucleotide transition on IL-10 and Sp1 gene expression in B cells, (iii) differences in Sp1 expression in periodontitis lesions from GG and AA genotype subjects and (iv) epigenetic modifications around the -1087 site and their influence on IL-10 gene expression. READ MORE