Search for dissertations about: "IL- 10"

Showing result 6 - 10 of 495 swedish dissertations containing the words IL- 10.

2. 6. Glucocorticosteroid effects on cytokine production: studies in a glucocorticosteroid resistance model and in allergic airway disease

   Author : Susanne Larsson; allergologi och palliativ medicin Lungmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GM-CSF; cytokine; glucocorticoids; budesonide; IL-2; IL-4; IL-12; asthma; allergic rhinitis; allergic airway inflammation; Respiratory system; Andningsorganen;

   Abstract : Glucocorticosteroids (GCS) are potent anti-inflammatory drugs, probably due to inhibitory effects on cytokine production. However, a small number of asthma patients seem GCS-resistant. Pro-inflammatory cytokines, such as interleukin-2(IL-2) and IL-4, produced during allergic airway inflammation have been proposed to induce the resistance to GCS. READ MORE

4. 7. The B lymphocyte in Staphylococcus aureus arthritis

   Author : Inger Gjertsson; Göteborgs universitet; []
   Keywords : Staphylococcus aureus; mice; arthritis; sepsis; B cells; Fcg receptors; CD22; ; IL-4; IL-10; IFN-g.;

   Abstract : Joint infection caused by Staphylococcus aureus leads to heavy synovitis and rapid destruction of bone and cartilage. Permanent loss of joint function is seen in 20-50% of the patients, despite early eradication of the bacteria with antibiotics. READ MORE

5. 8. Human genetic factors involved in immunity to Plasmodium falciparum infection

   Author : Manijeh Vafa Homann; Marita Troye-Blomberg; Marcel Hommel; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; Malaria; Immunity; Ethnic groups; Mali; Senegal; Genetic factors; IL-4; IL-10; Polymorphism; MOI; RBC variants; Immunology; Immunologi; immunologi; Immunology;

   Abstract : This study investigated the associations between IL-4 -590 C/T and IL-10 -1087 A/G polymorphisms and malariometric indexes in the Fulani and the Dogon ethnic groups living in sympatry in Mali and differing in susceptibility to malaria. The correlations between antibodies level and parasitological data as well as splenomegaly were assessed. READ MORE

6. 9. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

   Author : Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

   Abstract : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. READ MORE

7. 10. Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients

   Author : Madeleine Ingelsten; Göteborgs universitet; []
   Keywords : kidney transplantation; liver tolerance; HLA antibodies; dendritic cells; indoleamine 2; 3-dioxygenase; IL-10; natural killer cells;

   Abstract : Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance of receiving a kidney transplant. READ MORE