Search for dissertations about: "IL-1β"

Showing result 21 - 25 of 164 swedish dissertations containing the word IL-1β.

  2. 21. Cytokine-induced beta-cell apoptosis and its regulation by SOCS-1 and imidazoline compounds

    Author : Irina Zaitseva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A selective destruction of pancreatic β-cells as a consequence of inflammation in the islets of Langerhans is a feature of type 1 diabetes. Pro-inflammatory cytokines secreted by T lymphocytes and macrophages infiltrating the pancreatic islets participate in the development of this autoimmune disease by acting directly on the β-cell. READ MORE

  4. 22. Hormonal regulation of immune modulators in human breast tissue

    Author : Vivian Morad; Charlotta Dabrosin; Christina Ekerfelt; Malin Sund; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Breast cancer is the most common form of cancer and the second leading cause of malignancy-associated death in women worldwide. Estrogens are the main sex hormones in women. READ MORE

  5. 23. Anti-Collagen Type II Autoantibodies in an Acute Phenotype of Early Rheumatoid Arthritis

    Author : Mohammed Mullazehi; Johan Rönnelid; Bosse Nilsson; Kutty Selva Nandakumar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease with systemic inflammatory features that primarily affects small peripheral joints. Type II collagen (CII), is the most abundant collagen type in joint cartilage. Antibodies against CII (anti-CII) are found in a subpopulation of RA patients. READ MORE

  6. 24. Regulation of cytokine-induced nitric oxide production in insulin-producing cells

    Author : Malin Flodström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pancreatic islets; insulin-producing cells; cytokines; nitric oxide; inducible nitric oxide synthase; nuclear factor-kappaB; interferon regulatory factor-1; arginine; citrulline; argininosuccinate synthetase; insulin release; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Cytokine-induced expression of the inducible form of nitric oxide synthase (iNOS) and production of nitric oxide (NO) may contribute to pancreatic β-cell damage during the development of type 1 diabetes. iNOS catalyses the conversion of arginine into citrulline and NO, a reaction regulated by the amount of expressed iNOS enzyme and by the cellular availability of arginine. READ MORE

  7. 25. Monocyte and Neutrophil Inflammatory Responses to the Periodontopathogen Porphyromonas gingivalis

    Author : Kartheyaene Jayaprakash; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Anders Johansson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; Neutrophils; Porphyromonas gingivalis; Gingipains; Biomedicin; Biomedicine;

    Abstract : Periodontitis is one of the most common adult infections. Duing bacteremia in healthy individuals or patients with chronic periodontitis, a number of oral bacteria such as Porphyromonas gingivalis encounter inflammatory cells in the blood eg. platelets, neutrophils and monocytes. READ MORE