Search for dissertations about: "IL-1 Ra"

Showing result 6 - 10 of 18 swedish dissertations containing the words IL-1 Ra.

2. 6. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course

   Author : Alf Kastbom; Thomas Skogh; Peter Söderkvist; Alex Karlsson-Parra; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; autoantibodies; single-nucleotide polymorphisms; disease course; Rheumatology; Reumatologi;

   Abstract : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. READ MORE

4. 7. Pain and radiographic changes of the arthritic temporomandibular joint : relation to cytokines in synovial fluid and plasma

   Author : Silvi Nordahl; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Arthritis; Bone loss; Interleukin- 1 beta; Pain; Plasma; Progression; Radiographic changes; Synovial fluid; Temporomandibular joint; Tumor Necrosis Factor alpha;

   Abstract : In patients with rheumatoid arthritis and other inflammatory joint diseases, radiographic changes of the TMJ are frequently observed. Common symptoms of TMJ involvement are pain at rest and on movement of the jaw. READ MORE

5. 8. Cytokines and cytokine-directed intervention in experimental arthritis

   Author : Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
   Keywords : pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

   Abstract : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. READ MORE

6. 9. Cytokines in rheumatoid arthritis

   Author : Ann-Kristin Ulfgren; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Rheumatoid arthritis; Synovitis; Immunohistochemistry; Digital image analysis; Cytokine Therapy; TNF neutralisation; Arthroscopy;

   Abstract : Rheumatoid arthritis (RA) is a chronic systemic disease characterised by inflammation in several joints. Cytokines appear to be important as both disease promoting and disease- suppressing mediators in the disease. READ MORE

7. 10. Rheumatoid Arthritis in a 10-Year Perspective, Outcome for Patients Followed from Early Disease

   Author : Elisabet Lindqvist; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reumatologi; muskelsystem; rheumatology locomotion; Skelett; COMP; Skeleton; muscle system; Anti-IL-1alpha; Anti-CCP; Rheumatoid factor isotypes; Mortality; Radiographic progression; Joint damage; Disease activity; HAQ; SOFI; Disability; Prognosis; Rheumatoid arthritis; Outcome;

   Abstract : Rheumatoid arthritis (RA) is characterized by persistent inflammation, progressive joint damage and disability. This thesis describes the outcome after 10 years in a cohort of 183 RA patients (116 women, 67 men) recruited 1985-89. The mean age was 51 years and symptom duration 11 months at inclusion. READ MORE