Search for dissertations about: "IL-2"

Showing result 16 - 20 of 199 swedish dissertations containing the word IL-2.

  2. 16. Immunological studies of adenoids in children : relation to atopy

    Author : Georgios Papatziamos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adenoids; atopy; flow cytometry; immunohistochemistry; IgE; IL-2; IL-4; IFN-gamma; epsilonGL transcripts; IgE cells; IgE plasma cells;

    Abstract : The nasopharyngeal tonsil or adenoids is in constant interaction with our environment with every breath we take. This organ, rich in B cells, contains all the immunocompetent cells necessary for an interaction with T cells, exerted through secretion of cytokines and resulting in the production of immunoglobulins and the formation of memory cells. READ MORE

  4. 17. Activation of murine cytotoxic cells with interelukin-2 and the bacterial superantigen staphylococcal entertoxin A

    Author : Hans Belfrage; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; Immunology; cytokine; tolerance; LAK; NK; serologi; CTL; Staphylococcal enterotoxin A; SEA; Interleukin-2; murine; deletion; anergy;

    Abstract : Natural killer (NK) cells and T lymphocytes are the major effector cells that can recognize and kill tumor cells. NK cells have a constitutive cytotoxic activity and kill a wide spectrum of tumor cells while T cells recognize specific tumor antigens and need to be activated through their TCR to differentiate into cytotoxic T lymphocyte (CTL) killers or T helper cells. READ MORE

  5. 18. Genetic modification of human natural killer cells and possible applications thereof

    Author : Kyriakos Konstantinidis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Natural killer cells; retroviral transduction; interleukin-2; endoplasmic reticulum targeting; green fluorescent protein; multiple myeloma;

    Abstract : Natural killer (NK) cells are dependent on the presence of interleukin-2 (IL-2) for their survival and for their cytotoxicity against tumor cells. Currently, for in vitro expansion of NK cells from peripheral blood mononuclear cells (PBMCs), IL-2 is of great importance. READ MORE

  6. 19. Defensins and cytokines in inflammatory bowel disease

    Author : Arman Rahman; Mats Andersson; Umeå universitet; []
    Keywords : immunologi; Immunology;

    Abstract : Ulcerative colitis (UC) and Crohn’s disease (CD) constitute the two major inflammatory bowel diseases in man. Both are serious chronic illnesses of the intestine with severe debilitating effects. The etiology of the diseases is unknown, but involvement of both adaptive and innate immune reactions seems to be major factors in the pathogenesis. READ MORE

  7. 20. Regulation of T cells in Atherosclerosis

    Author : Megan Mulholland; Kardiovaskulär forskning - cellulär metabolism och inflammation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Atherosclerosis, the underlying pathology of cardiovascular diseases such as myocardial infarction and ischemic stroke, is characterized by chronic inflammation. T cells are present in atherosclerotic plaques and have been implicated in its pathogenesis. READ MORE