Search for dissertations about: "IL-35"
Found 3 swedish dissertations containing the word IL-35.
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1. Regulatory T cells in type 1 diabetes: the role of IL-35 in counteracting the disease
Abstract : Type 1 diabetes (T1D) is etiologically considered as an autoimmune disease, where insulin-producing β-cells are damaged by autoimmune attacks. Regulatory T (Treg) cells are immune homeostasis cells. In the present thesis I aimed to investigate the role of Treg cells and other immune cells in the early development of T1D. READ MORE
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2. Immunological strategies for counteracting type 1 diabetes focusing on IL-35 producing regulatory immune cells
Abstract : Type 1 diabetes (T1D) is an autoimmune disease where pancreatic β-cells are attacked by immune cells. Regulatory T (Treg) cells play critical roles in suppressing immune responses and their involvement have been intensively studied in T1D. Low dose IL-2 has been proposed to selectively boost Treg cells in T1D, with only limited success. READ MORE
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3. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages
Abstract : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). READ MORE