Search for dissertations about: "IL-6 and neurodegeneration"
Showing result 1 - 5 of 8 swedish dissertations containing the words IL-6 and neurodegeneration.
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1. A peripheral immune response in Huntington's disease and delineation of its importance in disease pathology
Abstract : Huntington’s disease (HD) is a fatal, hereditary disease for which there is no cure. It is caused by a mutation in a gene called huntingtin. HD is a so-called neurodegenerative disease, where there is a loss of neurons in areas of the brain that control body movements. This results in uncontrolled dance-like movements (chorea). READ MORE
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2. On inflammatory cytokines and β-amyloid peptides in acute and chronic neurodegeneration
Abstract : Insults to the brain as well as neurodegenerative diseases are known to elicit inflammatory responses. Inflammation in the brain can on one hand initiate processes that are harmful to the injured tissue and exacerbate the damage, leading to neuronal degeneration and glial activation, and on the other hand activate processes that may be necessary for repair mechanisms and regeneration. READ MORE
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3. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells
Abstract : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. READ MORE
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4. Studies on apolipoprotein E and high cholesterol diet as risk factors for neurodegeneration
Abstract : Elevated level of plasma cholesterol is a well-established risk factor for cardiovascular disease, and emerging evidence suggest that it plays a role in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD). The relations between dietary habits and neurodegeneration are complex, as the brain is selectively separated from peripheral circulation by the blood brain barrier (BBB). READ MORE
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5. Sickness behavior : immune system influences on brain and behavior
Abstract : Sickness behavior is a motivational state that redirects the needs and priorities of the organism during infection to aid recovery. The behavioral changes include fatigue, lowered mood and aches. READ MORE